Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9865337 | 0.78 | HSP90AA1 (0.32) | MAPT | |
| SCHEMBL9866361 | 0.77 | KMT2A (0.35) | KDM4ECYP1A2CYP2C19MAPT | |
| SCHEMBL9866727 | 0.76 | NFE2L2 (0.34) | KDM4ECYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL9866776 | 0.76 | SMN1; SMN2 (0.37) | KDM4EMAPT | |
| SCHEMBL9869170 | 0.74 | KDM4E (0.35) | KDM4ECYP1A2CYP3A4CYP2C19MAPT | |
| SCHEMBL12319048 | 0.72 | LOX (0.41) | MAPT | |
| SCHEMBL9865871 | 0.72 | L3MBTL1 (0.41) | — | |
| SCHEMBL10374044 | 0.71 | SMN1; SMN2 (0.36) | KDM4EMAPT | |
| SCHEMBL9376409 | 0.69 | CA2 (0.38) | — | |
| SCHEMBL11613284 | 0.69 | GRM4 (0.35) | KDM4ECYP1A2MAPTGRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4987141-A | DERIVATIVES OF BENZENE OR PYRIDINE HAVING SULFONATE AND SULFENYL, SULFONIMIDE OR SULFONAMIDE GROUPS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-01-22 | — | — | US | disclosed |
| EP-0356029-A2 | Insecticidal compounds | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-02-28 | — | — | EP | disclosed |