Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | QPCT | Q16769 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8590994 | 0.99 | KMT2A (0.50) | KMT2AMEN1HTTTP53MAPK1 | |
| SCHEMBL9260326 | 0.83 | MEN1 (0.72) | KMT2AMEN1HTTTP53MAPK1 | |
| SCHEMBL9266468 | 0.83 | MEN1 (0.72) | KMT2AMEN1HTTTP53MAPK1 | |
| SCHEMBL9260580 | 0.83 | MEN1 (0.72) | KMT2AMEN1HTTTP53MAPK1 | |
| SCHEMBL9267414 | 0.83 | MEN1 (0.72) | KMT2AMEN1HTTTP53MAPK1 | |
| SCHEMBL9285699 | 0.81 | KDM4E (0.70) | KMT2AMEN1HTTTP53MAPK1 | |
| SCHEMBL9266828 | 0.81 | ADRA2C (0.51) | KMT2AMEN1HTTTP53MAPK1 | |
| SCHEMBL10700909 | 0.78 | KMT2A (0.54) | KMT2AMEN1HTTTP53MAPK1 | |
| SCHEMBL8540598 | 0.75 | QPCT (0.53) | KMT2AMEN1TP53ATMKDM4E | |
| SCHEMBL9267886 | 0.73 | TBXAS1 (0.53) | KMT2AMEN1TP53MAPK1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991000858-A1 | PHARMACEUTICALLY ACTIVE COMPOUNDS | SCHERING CORPORATION (US) | 1991-01-24 | — | — | WO | disclosed |