Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 19/20 | 0.53 |
| ▸ | RXRB | P28702 | 11/20 | 0.52 |
| ▸ | RXRG | P48443 | 9/20 | 0.52 |
| ▸ | RARB | P10826 | 6/20 | 0.49 |
| ▸ | RARG | P13631 | 6/20 | 0.49 |
| ▸ | RARA | P10276 | 4/20 | 0.47 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CRABP2 | P29373 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8311698 | 0.84 | RXRA (0.52) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL9867927 | 0.82 | RXRA (0.71) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL9868551 | 0.75 | RXRA (0.55) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL7719786 | 0.74 | RXRA (0.72) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL8839257 | 0.74 | RXRA (0.69) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL8460878 | 0.72 | RXRA (0.70) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL8839140 | 0.72 | RXRA (0.65) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL7716684 | 0.72 | RXRA (0.67) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL8312104 | 0.71 | RXRA (0.57) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL1072441 | 0.69 | RXRA (1.00) | RXRARXRBRXRGRARBRARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE33533-E | Skin disorders | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES (CIRD) (FR) | 1991-02-05 | — | — | US | disclosed |
| US-4874747-A | DERMATOLOGY | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES (CIRD) (FR) | 1989-10-17 | — | — | US | disclosed |