Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 13/20 | 0.52 |
| ▸ | RARB | P10826 | 12/20 | 0.52 |
| ▸ | RARG | P13631 | 11/20 | 0.52 |
| ▸ | RXRB | P28702 | 10/20 | 0.52 |
| ▸ | RXRG | P48443 | 7/20 | 0.52 |
| ▸ | RARA | P10276 | 9/20 | 0.52 |
| ▸ | CYP26A1 | O43174 | 4/20 | 0.52 |
| ▸ | CYP26B1 | Q9NR63 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | GMNN | O75496 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8312104 | 0.85 | RXRA (0.57) | RXRARARBRARGRXRBRXRG | |
| SCHEMBL9869267 | 0.84 | RXRA (0.53) | RXRARARBRARGRXRBRXRG | |
| SCHEMBL846110 | 0.78 | RARB (0.81) | RXRARARBRARGRXRBRXRG | |
| SCHEMBL29827631 | 0.78 | RARB (0.81) | RXRARARBRARGRXRBRXRG | |
| SCHEMBL8460878 | 0.77 | RXRA (0.70) | RXRARARBRARGRXRBRXRG | |
| SCHEMBL8315054 | 0.77 | RXRA (0.52) | RXRARARBRARGRXRBRXRG | |
| Hydrochloric Acid SCHEMBL9120757 | 0.76 | RARB (0.78) | RXRARARBRARGRXRBRXRG | |
| Hydrazine SCHEMBL9430381 | 0.75 | RARB (0.76) | RXRARARBRARGRXRBRXRG | |
| SCHEMBL8839140 | 0.74 | RXRA (0.65) | RXRARARBRARGRXRBRXRG | |
| SCHEMBL8312210 | 0.74 | RXRA (0.32) | RXRACYP26A1CYP26B1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0963981-A1 | Biaryl heterocyclic aromatic compounds, pharmaceutical and cosmetic compositions containing them and uses thereof | Galderma Research & Development, S.N.C. (FR) | 1999-12-15 | — | — | EP | disclosed |