Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | MDM4 | O15151 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.41 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.40 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9869485 | 1.00 | MEN1 (0.46) | MEN1KMT2AMAPTTSHRLMNA | |
| SCHEMBL11533016 | 1.00 | MEN1 (0.46) | MEN1KMT2AMAPTTSHRLMNA | |
| SCHEMBL11462933 | 0.79 | TSHR (0.42) | MEN1KMT2AMAPTTSHRLMNA | |
| SCHEMBL11462932 | 0.79 | TSHR (0.42) | MEN1KMT2AMAPTTSHRLMNA | |
| SCHEMBL20109337 | 0.76 | MAPT (0.49) | MEN1KMT2AMAPTTSHRLMNA | |
| SCHEMBL20109332 | 0.76 | MEN1 (0.51) | MEN1KMT2AMAPTTSHRLMNA | |
| SCHEMBL5486359 | 0.75 | MAPT (0.48) | MEN1KMT2AMAPTLMNAMDM2 | |
| SCHEMBL5475595 | 0.75 | MAPT (0.48) | MEN1KMT2AMAPTLMNAMDM2 | |
| SCHEMBL5475589 | 0.75 | MAPT (0.48) | MEN1KMT2AMAPTLMNAMDM2 | |
| SCHEMBL8310392 | 0.75 | MEN1 (0.45) | MEN1KMT2AMAPTTSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0337945-A1 | Monoketo-pyrrolopyrroles | CIBA-GEIGY AG (CH) | 1989-10-18 | — | — | EP | claimed |
| US-5017706-A | Colorants for polymers | CIBA-GEIGY CORPORATION (US) | 1991-05-21 | — | — | US | disclosed |
| EP-0337945-A1 | Monoketo-pyrrolopyrroles | CIBA-GEIGY AG (CH) | 1989-10-18 | — | — | EP | disclosed |
| US-4212974-A | POLYMER STABILIZERS | SANKYO COMPANY LIMITED (JP) | 1980-07-15 | — | — | US | disclosed |
| US-4125533-A | STABILIZERS | SANKYO CO. LTD. (JP) | 1978-11-14 | — | — | US | disclosed |
| US-4016168-A | STABILIZERS FOR POLYMERS | SANKYO COMPANY LIMITED (JA) | 1977-04-05 | — | — | US | disclosed |