Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 7/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | MDM2 | Q00987 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30009568 | 0.82 | LMNA (0.59) | KMT2AALDH1A1POLBCA12CA7 | |
| SCHEMBL8014335 | 0.81 | RAB9A (0.50) | MEN1KMT2ACTDSP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL226537 | 0.77 | MEN1 (0.59) | MEN1KMT2ACTDSP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL14890386 | 0.77 | NFKB1 (0.38) | MEN1KMT2AALDH1A1MAPTTSHR | |
| SCHEMBL11372177 | 0.76 | MEN1 (0.54) | MEN1KMT2ACTDSP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL11372184 | 0.76 | MEN1 (0.54) | MEN1KMT2ACTDSP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL9869485 | 0.76 | MEN1 (0.46) | MEN1KMT2AALDH1A1MAPTTSHR | |
| SCHEMBL11533016 | 0.76 | MEN1 (0.46) | MEN1KMT2AALDH1A1MAPTTSHR | |
| SCHEMBL9869478 | 0.76 | MEN1 (0.46) | MEN1KMT2AALDH1A1MAPTTSHR | |
| SCHEMBL7672001 | 0.75 | HCAR2 (0.50) | ALDH1A1MAPTTSHRCA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108821975-B | Hydrogenated phenanthrene derivative containing exocyclic double bond and preparation method thereof | 安徽师范大学 | 2021-01-05 | — | — | CN | claimed |
| CN-108821975-A | A kind of hydrogenation phenanthrene derivatives and preparation method thereof containing exocyclic double bond | 安徽师范大学 | 2018-11-16 | — | — | CN | claimed |
| CN-108821975-B | Hydrogenated phenanthrene derivative containing exocyclic double bond and preparation method thereof | 安徽师范大学 | 2021-01-05 | — | — | CN | disclosed |
| CN-108821975-A | A kind of hydrogenation phenanthrene derivatives and preparation method thereof containing exocyclic double bond | 安徽师范大学 | 2018-11-16 | — | — | CN | disclosed |
| CN-108821975-A | A kind of hydrogenation phenanthrene derivatives and preparation method thereof containing exocyclic double bond | 安徽师范大学 | 2018-11-16 | — | — | CN | disclosed |
| US-20180118770-A1 | N-Heterocyclic Phosphines | THE BOARD OF REGENTS OF THE NEVADA SYSTEM OF HIGHER EDUCATION ON BEHALF OF THE UNIVERSITY OF NEVADA, LAS VEGAS | 2018-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180118770-A1 | N-Heterocyclic Phosphines | NANP, PPIP5K2, PHPT1 | MEN1 469/4885KMT2A 2508/4885CTDSP1 605/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.