Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 9/20 | 0.38 |
| ▸ | EPAS1 | Q99814 | 8/20 | 0.38 |
| ▸ | SCD | O00767 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5304916 | 0.81 | HIF1A (0.46) | HIF1AEPAS1ALDH1A1CYP3A4HPGD | |
| SCHEMBL16865542 | 0.75 | HIF1A (0.42) | HIF1AEPAS1ALDH1A1CYP3A4HPGD | |
| SCHEMBL5308020 | 0.72 | SMN1; SMN2 (0.46) | HIF1AEPAS1ALDH1A1CYP3A4HPGD | |
| SCHEMBL22420303 | 0.72 | HIF1A (0.46) | HIF1AEPAS1TDP1 | |
| SCHEMBL9582367 | 0.72 | HIF1A (0.45) | HIF1AEPAS1ALDH1A1CYP3A4HPGD | |
| SCHEMBL7766906 | 0.70 | ALDH1A1 (0.42) | HIF1AEPAS1ALDH1A1CYP3A4HPGD | |
| SCHEMBL4174656 | 0.70 | CTNNB1 (0.47) | SCDCYP3A4 | |
| SCHEMBL5499257 | 0.69 | ALDH1A1 (0.42) | HIF1AEPAS1ALDH1A1CYP3A4HPGD | |
| SCHEMBL2781380 | 0.69 | ACP3 (0.42) | SCD | |
| SCHEMBL4075729 | 0.69 | ACP3 (0.44) | SCDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5043344-A | Unsaturated N-benzopyranyllactams | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-08-27 | — | — | US | disclosed |
| EP-0337179-A1 | Unsaturated N-benzopyranyllactams | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-10-18 | — | — | EP | disclosed |