Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.66 |
| ▸ | POLB | P06746 | 1/20 | 0.66 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.66 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.66 |
| ▸ | HPGD | P15428 | 5/20 | 0.66 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.66 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | PIM1 | P11309 | 2/20 | 0.52 |
| ▸ | TOP2A | P11388 | 4/20 | 0.47 |
| ▸ | TOP1 | P11387 | 3/20 | 0.47 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.46 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10371828 | 0.99 | KDM4E (0.65) | KDM4EALDH1A1POLBHSP90AA1RXFP1 | |
| SCHEMBL10374981 | 0.92 | HPGD (0.75) | KDM4EALDH1A1POLBHSP90AA1RXFP1 | |
| SCHEMBL9869685 | 0.92 | LMNA (0.68) | KDM4EALDH1A1POLBHSP90AA1RXFP1 | |
| SCHEMBL10371959 | 0.92 | KDM4E (0.64) | KDM4EALDH1A1POLBHSP90AA1RXFP1 | |
| SCHEMBL10374985 | 0.91 | HPGD (0.74) | KDM4EALDH1A1POLBHSP90AA1RXFP1 | |
| SCHEMBL10372535 | 0.91 | KDM4E (0.62) | KDM4EALDH1A1POLBHSP90AA1RXFP1 | |
| SCHEMBL10373830 | 0.91 | TOP2A (0.57) | KDM4EALDH1A1POLBHSP90AA1RXFP1 | |
| SCHEMBL10372198 | 0.91 | HPGD (0.55) | KDM4EALDH1A1POLBHSP90AA1RXFP1 | |
| SCHEMBL9870203 | 0.91 | KDM4E (0.66) | KDM4EALDH1A1POLBHSP90AA1RXFP1 | |
| SCHEMBL9870059 | 0.90 | KDM4E (0.71) | KDM4EALDH1A1POLBHSP90AA1RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4981854-A | BACTERICIDES, ANIMAL GROWTH REGUALTORS | BAYER AKTIENGESELLSCHAFT (DE) | 1991-01-01 | — | — | US | disclosed |
| US-4980353-A | BACTERICIDES, ANIMAL GROWTH REGULATORS | BAYER AKTIENGESELLSCHAFT (DE) | 1990-12-25 | — | — | US | disclosed |
| EP-0154780-B1 | QUINOLINE ANTIBACTERIAL COMPOUNDS | ABBOTT LABORATORIES (US) | 1990-04-11 | — | — | EP | disclosed |
| EP-0154780-A1 | Quinoline antibacterial compounds | ABBOTT LABORATORIES (US) | 1985-09-18 | — | — | EP | disclosed |