Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.71 |
| ▸ | POLB | P06746 | 1/20 | 0.71 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.71 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.71 |
| ▸ | HPGD | P15428 | 5/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.65 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | TOP2A | P11388 | 6/20 | 0.47 |
| ▸ | TOP1 | P11387 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.46 |
| ▸ | TOP2B | Q02880 | 2/20 | 0.45 |
| ▸ | ALB | P02768 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10913495 | 0.91 | KDM4E (0.59) | KDM4EALDH1A1POLBHSP90AA1RXFP1 | |
| SCHEMBL9869629 | 0.90 | KDM4E (0.66) | KDM4EALDH1A1POLBHSP90AA1RXFP1 | |
| Hydrochloric Acid SCHEMBL9870987 | 0.90 | KDM4E (0.58) | KDM4EALDH1A1POLBHSP90AA1RXFP1 | |
| SCHEMBL10371828 | 0.89 | KDM4E (0.65) | KDM4EALDH1A1POLBHSP90AA1RXFP1 | |
| SCHEMBL10374981 | 0.89 | HPGD (0.75) | KDM4EALDH1A1POLBHSP90AA1RXFP1 | |
| SCHEMBL10371959 | 0.88 | KDM4E (0.64) | KDM4EALDH1A1POLBHSP90AA1RXFP1 | |
| SCHEMBL10374985 | 0.88 | HPGD (0.74) | KDM4EALDH1A1POLBHSP90AA1RXFP1 | |
| SCHEMBL10913414 | 0.88 | KDM4E (0.55) | KDM4EALDH1A1POLBHSP90AA1RXFP1 | |
| SCHEMBL9869480 | 0.84 | ALDH1A1 (0.72) | KDM4EALDH1A1POLBHSP90AA1RXFP1 | |
| SCHEMBL10913133 | 0.82 | KDM4E (0.64) | KDM4EALDH1A1POLBHSP90AA1RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0201829-A1 | 1-Aryl-4-quinolone-3-carboxylic acids | BAYER AG (DE) | 1986-11-20 | — | — | EP | claimed |
| US-4981854-A | BACTERICIDES, ANIMAL GROWTH REGUALTORS | BAYER AKTIENGESELLSCHAFT (DE) | 1991-01-01 | — | — | US | disclosed |
| US-4980353-A | BACTERICIDES, ANIMAL GROWTH REGULATORS | BAYER AKTIENGESELLSCHAFT (DE) | 1990-12-25 | — | — | US | disclosed |
| EP-0201829-A1 | 1-Aryl-4-quinolone-3-carboxylic acids | BAYER AG (DE) | 1986-11-20 | — | — | EP | disclosed |