Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.59 |
| ▸ | GAA | P10253 | 6/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.59 |
| ▸ | MEN1 | O00255 | 4/20 | 0.59 |
| ▸ | CA1 | P00915 | 2/20 | 0.59 |
| ▸ | CA2 | P00918 | 2/20 | 0.59 |
| ▸ | MITF | O75030 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | NPC1 | O15118 | 7/20 | 0.54 |
| ▸ | RAB9A | P51151 | 7/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | CRHBP | P24387 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9520101 | 1.00 | MAPT (0.59) | MAPTKMT2AGAASMN1; SMN2MEN1 | |
| SCHEMBL9869669 | 0.86 | MAPT (0.78) | MAPTKMT2AGAASMN1; SMN2MEN1 | |
| SCHEMBL9520088 | 0.86 | MAPT (0.78) | MAPTKMT2AGAASMN1; SMN2MEN1 | |
| SCHEMBL4172201 | 0.79 | MAPT (0.70) | MAPTKMT2AGAASMN1; SMN2MEN1 | |
| SCHEMBL4172197 | 0.79 | MAPT (0.70) | MAPTKMT2AGAASMN1; SMN2MEN1 | |
| SCHEMBL4747964 | 0.76 | CA1 (0.64) | MAPTKMT2AGAASMN1; SMN2MEN1 | |
| SCHEMBL4747962 | 0.76 | CA1 (0.64) | MAPTKMT2AGAASMN1; SMN2MEN1 | |
| SCHEMBL22235430 | 0.76 | CA1 (0.55) | MAPTKMT2ASMN1; SMN2MEN1CA1 | |
| SCHEMBL16039805 | 0.75 | RAB9A (0.62) | MAPTKMT2AGAASMN1; SMN2MEN1 | |
| SCHEMBL16039803 | 0.75 | RAB9A (0.62) | MAPTKMT2AGAASMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5072042-A | Skin disorders, anticarcinogenic-antitumor agent | BASF AKTIENGESELLSCHAFT (DE) | 1991-12-10 | — | — | US | disclosed |