Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.41 |
| ▸ | NAAA | Q02083 | 2/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | DAO | P14920 | 2/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | THRA | P10827 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | XIAP | P98170 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30706874 | 0.86 | CTBP2 (0.43) | CASP3CASP7MEN1ALDH1A1KMT2A | |
| SCHEMBL7436508 | 0.85 | ALDH1A1 (0.46) | HDAC2HDAC8HDAC6ALDH1A1KMT2A | |
| SCHEMBL3951320 | 0.84 | GLA (0.47) | CASP3CASP7TAAR1HDAC1HDAC6 | |
| SCHEMBL13941759 | 0.80 | IAPP (0.49) | ALDH1A1KDM4ELMNA | |
| SCHEMBL12290424 | 0.78 | NPSR1 (0.41) | TAAR1GPR84MEN1ALDH1A1KMT2A | |
| SCHEMBL5642127 | 0.77 | BACE1 (0.42) | NAAAFFAR4ALDH1A1 | |
| SCHEMBL3941260 | 0.76 | TRPM8 (0.47) | TAAR1HDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL3945233 | 0.75 | GLA (0.62) | MEN1ALDH1A1KMT2AKDM4E | |
| SCHEMBL5639921 | 0.74 | BACE1 (0.61) | TAAR1DAOHDAC1HDAC8 | |
| SCHEMBL28660694 | 0.73 | BACE1 (0.54) | HDAC8HDAC6MEN1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991011448-A1 | THERAPEUTIC AGENTS | THE BOOTS COMPANY PLC (GB) | 1991-08-08 | — | — | WO | disclosed |