Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.55 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.55 |
| ▸ | CA1 | P00915 | 2/20 | 0.52 |
| ▸ | CA2 | P00918 | 2/20 | 0.52 |
| ▸ | CA7 | P43166 | 2/20 | 0.52 |
| ▸ | CA9 | Q16790 | 2/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.52 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.47 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.47 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 2/20 | 0.42 |
| ▸ | MAOB | P27338 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9871313 | 0.94 | MTNR1A (0.50) | MTNR1AMTNR1BCA1CA2CA7 | |
| SCHEMBL1142445 | 0.87 | MTNR1A (0.53) | MTNR1AMTNR1BCA1CA2CA7 | |
| SCHEMBL22651499 | 0.84 | MTNR1A (0.46) | MTNR1AMTNR1BCA1CA2CA7 | |
| SCHEMBL18754954 | 0.84 | MTNR1A (0.53) | MTNR1AMTNR1BCA1CA2CA7 | |
| SCHEMBL9888683 | 0.84 | MTNR1A (0.53) | MTNR1AMTNR1BCA1CA2CA7 | |
| SCHEMBL11127176 | 0.82 | MTNR1A (0.56) | MTNR1AMTNR1BCA1CA2CA7 | |
| SCHEMBL10899564 | 0.82 | MTNR1A (0.51) | MTNR1AMTNR1BCA1CA2CA7 | |
| SCHEMBL9869523 | 0.81 | ACHE (0.44) | MTNR1AMTNR1BDRD2DRD3ACHE | |
| SCHEMBL418159 | 0.80 | CYP2C9 (0.52) | MTNR1AMTNR1BCA1CA2CA7 | |
| SCHEMBL11800930 | 0.80 | MTNR1A (0.44) | MTNR1AMTNR1BTAS1R3TAS1R1TAS1R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5043094-A | Optically active bisaryl compound | ADEKA ARGUS CHEMICAL CO., LTD. (JP) | 1991-08-27 | — | — | US | claimed |
| US-5043094-A | Optically active bisaryl compound | ADEKA ARGUS CHEMICAL CO., LTD. (JP) | 1991-08-27 | — | — | US | disclosed |