Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 7/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.41 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | PKM | P14618 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10871764 | 0.98 | GAA (0.50) | GAAMAPTLMNAMEN1KMT2A | |
| SCHEMBL10362980 | 0.94 | GAA (0.49) | GAAMAPTLMNAMEN1KMT2A | |
| SCHEMBL9869292 | 0.91 | GAA (0.56) | GAAMAPTLMNAMEN1KMT2A | |
| SCHEMBL9870547 | 0.84 | GAA (0.52) | GAAMAPTLMNAMEN1KMT2A | |
| SCHEMBL9870322 | 0.83 | GAA (0.47) | GAAMAPTLMNAMEN1KMT2A | |
| SCHEMBL10363066 | 0.82 | GAA (0.46) | GAAMAPTLMNAMEN1KMT2A | |
| SCHEMBL10364460 | 0.79 | ALDH1A1 (0.52) | GAAMAPTLMNAMEN1KMT2A | |
| SCHEMBL9869467 | 0.77 | MAPT (0.45) | GAAMAPTLMNAMEN1KMT2A | |
| SCHEMBL10384154 | 0.76 | KCNMA1 (0.41) | GAAMAPTLMNAMEN1KMT2A | |
| SCHEMBL10364662 | 0.76 | MAPT (0.56) | GAAMAPTLMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4992471-A | Fluorinated carboxanilide | LILLY INDUSTRIES LIMITED (GB) | 1991-02-12 | — | — | US | disclosed |
| EP-0201193-B1 | CARBOXANILIDES | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1990-10-24 | — | — | EP | disclosed |
| EP-0238351-A2 | Molluscicides | LILLY INDUSTRIES LIMITED (GB) | 1987-09-23 | — | — | EP | disclosed |
| EP-0201193-A2 | Carboxanilides | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1986-11-12 | — | — | EP | disclosed |
| EP-0201194-A2 | Diabrotica larvicidal agents | ELI LILLY AND COMPANY (US) | 1986-11-12 | — | — | EP | disclosed |