Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | PKLR | P30613 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | DAGLA | Q9Y4D2 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | PLCG2 | P16885 | 1/20 | 0.40 |
| ▸ | GHSR | Q92847 | 1/20 | 0.40 |
| ▸ | ABHD6 | Q9BV23 | 2/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.40 |
| ▸ | COXFA4 | O00483 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9293231 | 0.79 | MAOB (0.46) | HTR6PKMMAPTTP53RXFP1 | |
| SCHEMBL9521842 | 0.77 | HTR6 (0.42) | HTR6PKMMAPTTP53RXFP1 | |
| SCHEMBL9293420 | 0.76 | TLR3 (0.44) | HTR6PKMMAPTTP53RXFP1 | |
| SCHEMBL577986 | 0.76 | BCHE (0.49) | OPRM1PDE4DMAPTPLCG2GHSR | |
| SCHEMBL12569163 | 0.73 | KMT2A (0.44) | OPRM1PDE4DDAGLAMAPTABHD6 | |
| SCHEMBL9294310 | 0.72 | HIF1A (0.48) | HTR6 | |
| SCHEMBL10704500 | 0.72 | HTR2C (0.57) | HTR6CYP3A4 | |
| SCHEMBL546729 | 0.71 | BCHE (0.65) | OPRM1PDE4DPDE10ACOXFA4 | |
| SCHEMBL29401664 | 0.71 | BCHE (0.65) | OPRM1PDE4DPDE10ACOXFA4 | |
| SCHEMBL9294550 | 0.71 | HTR6 (0.45) | HTR6PKMMAPTTP53RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5043344-A | Unsaturated N-benzopyranyllactams | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-08-27 | — | — | US | disclosed |
| EP-0337179-A1 | Unsaturated N-benzopyranyllactams | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-10-18 | — | — | EP | disclosed |