Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.54 |
| ▸ | BACE1 | P56817 | 2/20 | 0.46 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ACVR1 | Q04771 | 3/20 | 0.40 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.40 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.40 |
| ▸ | CSF1R | P07333 | 1/20 | 0.40 |
| ▸ | PRKACA | P17612 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11009860 | 0.81 | BACE1 (0.62) | IDO1BACE1EGLN2NPC1RAB9A | |
| SCHEMBL11010979 | 0.71 | SMN1; SMN2 (0.58) | BACE1EGLN2KDM4EGAAMAPT | |
| SCHEMBL9869687 | 0.69 | BACE1 (0.68) | IDO1BACE1EGLN2KDM4EGAA | |
| SCHEMBL9870329 | 0.67 | TUBB4A (0.53) | EGLN2KDM4EMAPTALDH1A1HPGD | |
| SCHEMBL9870207 | 0.66 | KDM4E (0.49) | BACE1EGLN2KDM4EGAAMAPT | |
| SCHEMBL25296092 | 0.64 | BACE1 (0.70) | BACE1KDM4ENPC1RAB9AGAA | |
| SCHEMBL3036429 | 0.63 | EGLN2 (0.49) | BACE1EGLN2KDM4ERAB9AGAA | |
| SCHEMBL6217374 | 0.63 | EGLN2 (0.41) | IDO1BACE1EGLN2ACVR1CHEK1 | |
| SCHEMBL2396066 | 0.63 | EGLN2 (0.41) | BACE1EGLN2RAB9AACVR1CHEK1 | |
| SCHEMBL7903223 | 0.63 | EGLN2 (0.41) | BACE1EGLN2ACVR1CHEK1DYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5072042-A | Skin disorders, anticarcinogenic-antitumor agent | BASF AKTIENGESELLSCHAFT (DE) | 1991-12-10 | — | — | US | claimed |
| US-5037980-A | Anxiolytic agents, hypotensive agents | AMERICAN CYANAMID COMPANY (US) | 1991-08-06 | — | — | US | disclosed |