Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDH1 | P40925 | 2/20 | 0.46 |
| ▸ | MDH2 | P40926 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | USP2 | O75604 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | APAF1 | O14727 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 3/20 | 0.42 |
| ▸ | RAD52 | P43351 | 3/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | UBE2N | P61088 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8413301 | 0.86 | LMNA (0.46) | MDH1MDH2LMNACYP2D6TSHR | |
| SCHEMBL68023 | 0.85 | SMN1; SMN2 (0.44) | MDH1MDH2LMNACYP2D6TSHR | |
| SCHEMBL11129443 | 0.85 | LMNA (0.56) | MDH1MDH2LMNACYP2D6TSHR | |
| SCHEMBL9293574 | 0.85 | LMNA (0.48) | MDH1MDH2LMNACYP2D6TSHR | |
| SCHEMBL4894447 | 0.83 | ESR1 (0.43) | LMNACYP2D6TSHRTDP1CYP1A2 | |
| SCHEMBL6152034 | 0.83 | SHBG (0.43) | MDH1MDH2LMNACYP2D6TSHR | |
| SCHEMBL18998946 | 0.80 | LMNA (0.49) | MDH1MDH2LMNACYP2D6TSHR | |
| SCHEMBL8749528 | 0.80 | TSHR (0.45) | MDH1MDH2LMNACYP2D6TSHR | |
| SCHEMBL9869881 | 0.77 | SHBG (0.38) | MDH1MDH2LMNACYP2D6TSHR | |
| SCHEMBL10511423 | 0.76 | LMNA (0.46) | MDH1MDH2LMNACYP2D6TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5051342-A | Sharpness, whiteness | FUJI PHOTO FILM CO., LTD. (JP) | 1991-09-24 | — | — | US | disclosed |
| US-4880726-A | TRANSMITTING LIGHT THROUGH A BAND STOP FILTER; REDUCED COLOR MIXING | FUJI PHOTO FILM CO., LTD. (JP) | 1989-11-14 | — | — | US | disclosed |