Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.75 |
| ▸ | LMNA | P02545 | 5/20 | 0.75 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.75 |
| ▸ | TP53 | P04637 | 1/20 | 0.75 |
| ▸ | NPC1 | O15118 | 7/20 | 0.55 |
| ▸ | RAB9A | P51151 | 7/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.55 |
| ▸ | HTT | P42858 | 6/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | PAX8 | Q06710 | 5/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | MITF | O75030 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | JAK2 | O60674 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9869949 | 1.00 | ALDH1A1 (0.75) | ALDH1A1LMNASMN1; SMN2TP53NPC1 | |
| SCHEMBL8922653 | 0.86 | ALDH1A1 (0.54) | ALDH1A1LMNASMN1; SMN2TP53NPC1 | |
| Propachlor SCHEMBL1701162 | 0.86 | ALDH1A1 (1.00) | ALDH1A1LMNASMN1; SMN2TP53NPC1 | |
| Propachlor SCHEMBL65571 | 0.86 | ALDH1A1 (1.00) | ALDH1A1LMNASMN1; SMN2TP53NPC1 | |
| SCHEMBL20421705 | 0.84 | ALDH1A1 (0.53) | ALDH1A1LMNASMN1; SMN2TP53NPC1 | |
| SCHEMBL29131651 | 0.83 | ALDH1A1 (0.51) | ALDH1A1LMNASMN1; SMN2TP53NPC1 | |
| SCHEMBL6623670 | 0.83 | ALDH1A1 (0.51) | ALDH1A1LMNASMN1; SMN2TP53NPC1 | |
| SCHEMBL11382770 | 0.81 | ALDH1A1 (0.73) | ALDH1A1LMNASMN1; SMN2TP53NPC1 | |
| SCHEMBL9555055 | 0.81 | ALDH1A1 (0.50) | ALDH1A1LMNASMN1; SMN2TP53NPC1 | |
| SCHEMBL11250766 | 0.80 | ALDH1A1 (0.53) | ALDH1A1LMNASMN1; SMN2TP53NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4988820-A | Inhibiting platelet aggregation, anticoagulants, thromboxane a2 antagonist | BAYER AKTIENGESELLSCHAFT (DE) | 1991-01-29 | — | — | US | disclosed |
| US-4965258-A | Anticoagulant; thromboxane a2 antagonist | BAYER AKTIENGESELLSCHAFT (DE) | 1990-10-23 | — | — | US | disclosed |
| US-4904797-A | REACTING A (BENZENESULFONAMIDOALKYL)CYCLOALKANO(1,2-B)INDOLE WITH ACRYLONITRILE; HYDROLYSIS, HYDROGENATION, REDUCTION | BAYER AKTIENGESELLSCHAFT (DE) | 1990-02-27 | — | — | US | disclosed |
| US-4827032-A | INTERMEDIATES FOR ANTICOAGULANTS | BAYER AKTIENGESELLSCHAFT (DE) | 1989-05-02 | — | — | US | disclosed |
| US-4055663-A | Halogenated acylamino acids as fungicides | NATIONAL PATENT DEVELOPMENT CORPORATION (US) | 1977-10-25 | — | — | US | disclosed |