SCHEMBL9869971

SCHEMBL9869971

CCN(CC)C(=O)c1sc(Cl)nc1C(F)(F)F

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.42
KMT2A Q03164 1/20 0.42
CRHR1 P34998 3/20 0.42
CD274 Q9NZQ7 1/20 0.40
ALDH1A1 P00352 5/20 0.37
MAPT P10636 4/20 0.37
TSHR P16473 2/20 0.37
HPGD P15428 1/20 0.37
AHR P35869 1/20 0.36
MLYCD O95822 1/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
POLB P06746 1/20 0.36
RORC P51449 1/20 0.35
HTT P42858 1/20 0.35
MAPK1 P28482 1/20 0.35
HSD17B10 Q99714 1/20 0.35
HCRTR1 O43613 1/20 0.34
HCRTR2 O43614 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
NPC1 O15118 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1778181 0.77 ALDH1A1 (0.55) MEN1KMT2AALDH1A1MAPTTSHR
SCHEMBL10820861 0.76 KMT2A (0.48) MEN1KMT2AALDH1A1MAPTTSHR
SCHEMBL2309900 0.76 ALDH1A1 (0.51) MEN1KMT2AALDH1A1MAPTHPGD
SCHEMBL10712414 0.76 MAPT (0.46) MEN1KMT2ACRHR1ALDH1A1MAPT
SCHEMBL2310087 0.76 MEN1 (0.51) MEN1KMT2AALDH1A1MAPTTSHR
Hydrochloric Acid SCHEMBL10820945 0.75 ALDH1A1 (0.53) MEN1KMT2AALDH1A1MAPTTSHR
SCHEMBL2310145 0.75 MEN1 (0.49) MEN1KMT2AALDH1A1MAPTTSHR
SCHEMBL8551963 0.74 MEN1 (0.48) MEN1KMT2AALDH1A1MAPTTSHR
Hydrazine SCHEMBL9675518 0.74 ALDH1A1 (0.52) MEN1KMT2AALDH1A1MAPTTSHR
SCHEMBL10712503 0.74 MEN1 (0.48) MEN1KMT2AALDH1A1MAPTTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4602937-A PLANT SAFENING AGENTS, ACETAMIDE HERBICIDE MONSANTO COMPANY (US) 1986-07-29 US claimed
US-4992434-A Prevention of infestation of plants by phytopathogenic microorganisms CIBA-GEIGY CORPORATION (US) 1991-02-12 US disclosed
EP-0066830-B1 ONE-COMPONENT SYSTEM FOR PREPARING POLYURETHANE FOAMS WITH DIMENSIONAL STABILITY Henkel Kommanditgesellschaft auf Aktien (DE) 1986-08-13 EP disclosed
US-4602937-A PLANT SAFENING AGENTS, ACETAMIDE HERBICIDE MONSANTO COMPANY (US) 1986-07-29 US disclosed
US-4602454-A PLANT SAFENING AGENTS, SEEDS CHLOROACETAMIDE HERBICIDES MONSANTO COMPANY (US) 1986-07-29 US disclosed
US-4586948-A 2,4-disubstituted-5-thiazole-carboxylic acids and derivatives MONSANTO COMPANY (US) 1986-05-06 US disclosed
US-4437875-A PLANT SAFENING AGENT FOR ACETAMIDE HERBICIDE MONSANTO COMPANY (US) 1984-03-20 US disclosed
US-4437876-A PLANT SAFENING AGENTS FOR ACETAMIDE HERBICIDES MONSANTO COMPANY (US) 1984-03-20 US disclosed
US-4199506-A REDUCES HERBICIDAL INJURY TO PLATNS DUE TO ACETAMIDE HERBICIDES MONSANTO COMPANY (US) 1980-04-22 US disclosed