SCHEMBL2310145

SCHEMBL2310145

O=C(Cl)c1sc(Cl)nc1C(F)(F)F

nearest known ligand 0.49

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.49
KMT2A Q03164 2/20 0.49
MAPT P10636 4/20 0.40
ALDH1A1 P00352 3/20 0.40
HPGD P15428 1/20 0.40
TSHR P16473 1/20 0.40
AHR P35869 1/20 0.39
POLB P06746 1/20 0.36
HSD11B1 P28845 1/20 0.32
ATF1 P18846 1/20 0.31
NFKB1 P19838 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1778181 0.86 ALDH1A1 (0.55) MEN1KMT2AMAPTALDH1A1HPGD
Hydrochloric Acid SCHEMBL10820945 0.85 ALDH1A1 (0.53) MEN1KMT2AMAPTALDH1A1HPGD
SCHEMBL10712503 0.83 MEN1 (0.48) MEN1KMT2AMAPTALDH1A1HPGD
SCHEMBL8551963 0.83 MEN1 (0.48) MEN1KMT2AMAPTALDH1A1HPGD
Hydrazine SCHEMBL9675518 0.83 ALDH1A1 (0.52) MEN1KMT2AMAPTALDH1A1HPGD
SCHEMBL6137447 0.81 MAPT (0.37) MEN1KMT2AMAPTALDH1A1POLB
SCHEMBL883065 0.81 MAPT (0.37) MEN1KMT2AMAPTALDH1A1POLB
SCHEMBL2199155 0.79 MAPT (0.56) MEN1KMT2AMAPTALDH1A1HPGD
SCHEMBL28070522 0.79 ALDH1A1 (0.41) MEN1KMT2AMAPTALDH1A1HPGD
SCHEMBL10712926 0.79 MAPT (0.49) MEN1KMT2AMAPTALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4602937-A PLANT SAFENING AGENTS, ACETAMIDE HERBICIDE MONSANTO COMPANY (US) 1986-07-29 US claimed
EP-0044201-B1 2-CHLORO-4-TRIFLUOROMETHYL-THIAZOLECARBOTHIOIC ACIDS USEFUL AS HERBICIDAL SAFENERS MONSANTO COMPANY (US) 1984-09-26 EP claimed
EP-0044201-A1 2-Chloro-4-trifluoromethyl-thiazolecarbothioic acids useful as herbicidal safeners MONSANTO COMPANY (US) 1982-01-20 EP claimed
WO-2025085848-A1 ANTIBACTERIAL COMPOUNDS ARREPATH, INC. (US) 2025-04-24 WO disclosed
CN-104277032-B PESTICIDAL (HETERO) ARYLPYRROLIDINES 拜耳作物科学公司 2017-04-12 CN disclosed
EP-3095780-A1 PESTICIDAL ARYLPYRROLIDINES Bayer Intellectual Property GmbH (DE) 2016-11-23 EP disclosed
US-9271499-B2 Pesticidal arylpyrrolidines BAYER INTELLECTUAL PROPERTY GMBH (DE) 2016-03-01 US disclosed
US-9266830-B2 Pesticidal arylpyrrolidines BAYER INTELLECTUAL PROPERTY GMBH (DE) 2016-02-23 US disclosed
US-20150073139-A1 Pesticidal Arylpyrrolidines BAYER CROPSCIENCE AG (DE) 2015-03-12 US disclosed
US-20150011553-A1 Pesticidal Arylpyrrolidines BAYER CROPSCIENCE AG (DE) 2015-01-08 US disclosed
US-8785647-B2 Pesticidal arylpyrrolidines BAYER INTELLECTUAL PROPERTY GMBH (DE) 2014-07-22 US disclosed
US-4602454-A PLANT SAFENING AGENTS, SEEDS CHLOROACETAMIDE HERBICIDES MONSANTO COMPANY (US) 1986-07-29 US disclosed
US-4602937-A PLANT SAFENING AGENTS, ACETAMIDE HERBICIDE MONSANTO COMPANY (US) 1986-07-29 US disclosed
US-4586948-A 2,4-disubstituted-5-thiazole-carboxylic acids and derivatives MONSANTO COMPANY (US) 1986-05-06 US disclosed
EP-0044201-B1 2-CHLORO-4-TRIFLUOROMETHYL-THIAZOLECARBOTHIOIC ACIDS USEFUL AS HERBICIDAL SAFENERS MONSANTO COMPANY (US) 1984-09-26 EP disclosed
US-4437875-A PLANT SAFENING AGENT FOR ACETAMIDE HERBICIDE MONSANTO COMPANY (US) 1984-03-20 US disclosed
US-4437876-A PLANT SAFENING AGENTS FOR ACETAMIDE HERBICIDES MONSANTO COMPANY (US) 1984-03-20 US disclosed
EP-0044201-A1 2-Chloro-4-trifluoromethyl-thiazolecarbothioic acids useful as herbicidal safeners MONSANTO COMPANY (US) 1982-01-20 EP disclosed
US-4251261-A PLANT GROWTH REGULATORS; USE WITH HERBICIDAL 2-CHLORO-N-(2-METHOXY-1-METHYLETHYL)-6'-ETHYL-O-ACETOTOLUIDIDE MONSANTO COMPANY (US) 1981-02-17 US disclosed
US-4199506-A REDUCES HERBICIDAL INJURY TO PLATNS DUE TO ACETAMIDE HERBICIDES MONSANTO COMPANY (US) 1980-04-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150011553-A1 Pesticidal Arylpyrrolidines DDT, AADAC, AHR MEN1 3599/4885KMT2A 1019/4885MAPT 4207/4885
US-20150073139-A1 Pesticidal Arylpyrrolidines DDT, ACHE, QDPR MEN1 3163/4885KMT2A 749/4885MAPT 3780/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.