Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 12/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.38 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | ATP4A | P20648 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | HRH2 | P25021 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | ATP4B | P51164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9852504 | 1.00 | SMN1; SMN2 (0.40) | SMN1; SMN2ACHEMEN1SLC22A1ABCB11 | |
| SCHEMBL9852507 | 0.82 | SMN1; SMN2 (0.41) | SMN1; SMN2ACHEMEN1SLC22A1ABCB11 | |
| SCHEMBL9212163 | 0.77 | ACHE (0.38) | ACHEKMT2AHRH3BCHE | |
| SCHEMBL9219620 | 0.74 | ACHE (0.34) | ACHEBCHE | |
| SCHEMBL2068396 | 0.71 | SMN1; SMN2 (0.73) | SMN1; SMN2CYP2C19MAPTCHRNA1CHRNA3 | |
| SCHEMBL11707997 | 0.69 | SMN1; SMN2 (0.50) | SMN1; SMN2MEN1KMT2AMAPTCHRNA1 | |
| SCHEMBL11812000 | 0.69 | SMN1; SMN2 (0.50) | SMN1; SMN2MEN1KMT2AMAPTCHRNA1 | |
| SCHEMBL9216204 | 0.66 | ACHE (0.71) | ACHEMEN1SLC22A1ABCB11LMNA | |
| SCHEMBL9216213 | 0.66 | ACHE (0.71) | ACHEMEN1SLC22A1ABCB11LMNA | |
| SCHEMBL2067894 | 0.66 | SMN1; SMN2 (0.50) | SMN1; SMN2KMT2ACHRNA1CHRNA3CHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5075301-A | FURAN DERIVATIVES USEFUL FOR THE TREATMENT OF GASTRO-INTESTINAL DISORDERS | KYOWA HAKKO KOGYO, CO., LTD. (JP) | 1991-12-24 | — | — | US | disclosed |