SCHEMBL9870049

SCHEMBL9870049

CO[Si](C)(CCC1CCC2OC2C1)OC.CO[Si](CCCOCC1CO1)(OC)OC

nearest known ligand 0.39

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.38
ALDH1A1 P00352 1/20 0.37
TDP1 Q9NUW8 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14875824 0.97 TSHR (0.38) TSHRSMN1; SMN2ALDH1A1TDP1
SCHEMBL8571810 0.97 TSHR (0.38) TSHRSMN1; SMN2ALDH1A1TDP1
SCHEMBL2052975 0.94 TSHR (0.41) TSHRSMN1; SMN2ALDH1A1TDP1
SCHEMBL16666205 0.94 TSHR (0.41) TSHRSMN1; SMN2ALDH1A1TDP1
SCHEMBL8022971 0.92 TSHR (0.40) TSHRSMN1; SMN2ALDH1A1TDP1
SCHEMBL7088448 0.90 TSHR (0.38) TSHRSMN1; SMN2ALDH1A1TDP1
SCHEMBL14743070 0.89 SMN1; SMN2 (0.38) TSHRSMN1; SMN2ALDH1A1TDP1
SCHEMBL9868126 0.88 SMN1; SMN2 (0.37) TSHRSMN1; SMN2ALDH1A1TDP1
SCHEMBL3816987 0.88 SMN1; SMN2 (0.37) TSHRSMN1; SMN2ALDH1A1TDP1
SCHEMBL6694355 0.88 SMN1; SMN2 (0.39) TSHRSMN1; SMN2ALDH1A1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4988755-A Binder and protective coating to impart oxidation and corrosion resistance to powders; molding materials; motors; actuators THE B. F. GOODRICH COMPANY (US) 1991-01-29 US claimed