SCHEMBL9870067

SCHEMBL9870067

Cc1nonc1Cn1c(=O)sc2cc(F)c(N3C(=O)C4=C(CCCC4)C3=O)cc21

nearest known ligand 0.37

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
GRM7 Q14831 4/20 0.36
GRM4 Q14833 4/20 0.36
GRM1 Q13255 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9685668 0.83 MAPT (0.38) GRM7GRM4GRM1
SCHEMBL9685792 0.82 GRM7 (0.37) GRM7GRM4GRM1
SCHEMBL9687690 0.80 GRM7 (0.36) GRM7GRM4GRM1
SCHEMBL10365355 0.77 GRM7 (0.39) GRM7GRM4GRM1
SCHEMBL10365073 0.76 SHMT2 (0.41) GRM7GRM4GRM1
SCHEMBL10365372 0.76 GRM7 (0.37) GRM7GRM4GRM1
SCHEMBL10474023 0.76 SMN1; SMN2 (0.37)
SCHEMBL10365246 0.71 GRM7 (0.38) GRM7GRM4GRM1
SCHEMBL10514731 0.71 PPOX (0.52)
SCHEMBL29253166 0.67 GRM7 (0.38) GRM7GRM4GRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5077401-A Herbicides NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) 1991-12-31 US claimed