Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 3/20 | 0.61 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.61 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9819011 | 0.86 | SLC6A4 (0.54) | SLC6A4SLC6A3SIGMAR1 | |
| SCHEMBL9818974 | 0.83 | SLC6A4 (0.59) | SLC6A4SLC6A3SIGMAR1 | |
| SCHEMBL10357800 | 0.81 | SIGMAR1 (0.81) | SLC6A4SLC6A3SIGMAR1 | |
| SCHEMBL9818782 | 0.80 | SIGMAR1 (0.66) | SLC6A4SLC6A3SIGMAR1 | |
| Maleic Acid SCHEMBL10358287 | 0.80 | SLC6A4 (0.63) | SLC6A4SLC6A3SIGMAR1 | |
| Hydrochloric Acid SCHEMBL10574099 | 0.76 | SLC6A4 (0.61) | SLC6A4SLC6A3SIGMAR1 | |
| SCHEMBL9818977 | 0.76 | SLC6A4 (0.60) | SLC6A4SLC6A3SIGMAR1 | |
| SCHEMBL6255520 | 0.76 | SIGMAR1 (1.00) | SLC6A4SLC6A3SIGMAR1 | |
| SCHEMBL10357706 | 0.75 | SIGMAR1 (0.77) | SLC6A4SLC6A3SIGMAR1 | |
| Perastine SCHEMBL1506306 | 0.75 | CYP3A4 (0.83) | SLC6A4SLC6A3SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4983614-A | ANTISPASMODIC, ANTIALLERGENIC AND ANTIHISTAMINE AGENTS | LES LABORATOIRES MERAM (FR) | 1991-01-08 | — | — | US | claimed |