Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 18/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CETP | P11597 | 1/20 | 0.31 |
| ▸ | CEPT1 | Q9Y6K0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9206818 | 0.90 | AKR1B1 (0.57) | AKR1B1MEN1KMT2ACETPCEPT1 | |
| SCHEMBL9872250 | 0.81 | AKR1B1 (0.57) | AKR1B1MEN1KMT2A | |
| SCHEMBL9199051 | 0.79 | AKR1B1 (0.78) | AKR1B1MEN1KMT2A | |
| SCHEMBL9870079 | 0.76 | AKR1B1 (0.36) | AKR1B1MEN1KMT2A | |
| SCHEMBL9870990 | 0.75 | AKR1B1 (0.62) | AKR1B1MEN1KMT2A | |
| SCHEMBL9872192 | 0.73 | AKR1B1 (0.54) | AKR1B1 | |
| SCHEMBL9870643 | 0.73 | AKR1B1 (0.52) | AKR1B1 | |
| SCHEMBL9871499 | 0.73 | AKR1B1 (0.65) | AKR1B1 | |
| SCHEMBL9870131 | 0.72 | AKR1B1 (0.67) | AKR1B1 | |
| SCHEMBL9204824 | 0.71 | AKR1B1 (0.55) | AKR1B1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4996204-A | Antidiabetic agents | PFIZER INC. (US) | 1991-02-26 | — | — | US | disclosed |
| EP-0401981-A1 | Pyridazinone deriratives | PFIZER INC. (US) | 1990-12-12 | — | — | EP | disclosed |