Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 6/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9870990 | 0.79 | AKR1B1 (0.62) | AKR1B1MEN1KMT2A | |
| SCHEMBL9870150 | 0.76 | AKR1B1 (0.54) | AKR1B1MEN1KMT2A | |
| SCHEMBL9870869 | 0.76 | AKR1B1 (0.61) | AKR1B1 | |
| SCHEMBL9870468 | 0.75 | AKR1B1 (0.50) | AKR1B1RAB9ASMN1; SMN2 | |
| SCHEMBL9870702 | 0.72 | AKR1B1 (0.54) | AKR1B1 | |
| SCHEMBL9872250 | 0.71 | AKR1B1 (0.57) | AKR1B1MEN1KMT2A | |
| SCHEMBL9871583 | 0.71 | AKR1B1 (0.61) | AKR1B1 | |
| SCHEMBL9870810 | 0.71 | AKR1B1 (0.67) | AKR1B1 | |
| SCHEMBL9870728 | 0.70 | AKR1B1 (0.35) | AKR1B1 | |
| SCHEMBL9870643 | 0.68 | AKR1B1 (0.52) | AKR1B1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4996204-A | Antidiabetic agents | PFIZER INC. (US) | 1991-02-26 | — | — | US | disclosed |