Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | DHFR | P00374 | 1/20 | 0.40 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.40 |
| ▸ | GUSB | P08236 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | CACNA1D | Q01668 | 3/20 | 0.39 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.39 |
| ▸ | CACNA1S | Q13698 | 2/20 | 0.39 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.39 |
| ▸ | KIF11 | P52732 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9870854 | 0.90 | ALDH1A1 (0.43) | ALDH1A1CA1CA2LMNASMN1; SMN2 | |
| SCHEMBL9871899 | 0.81 | CACNA1F (0.60) | ALDH1A1LMNASMN1; SMN2ALOX12KMT2A | |
| SCHEMBL9871923 | 0.81 | ALDH1A1 (0.54) | ALDH1A1CA1CA2LMNASMN1; SMN2 | |
| SCHEMBL9869833 | 0.81 | CACNA1F (0.42) | ALDH1A1LMNACACNA1DCACNA1FCACNA1S | |
| SCHEMBL9870706 | 0.80 | ALDH1A1 (0.38) | ALDH1A1LMNASMN1; SMN2ALOX12HTT | |
| SCHEMBL9870418 | 0.80 | GAA (0.47) | ALDH1A1LMNASMN1; SMN2KMT2ADHFR | |
| SCHEMBL9869972 | 0.77 | ATM (0.43) | ALDH1A1LMNASMN1; SMN2KMT2AMAPT | |
| SCHEMBL9871298 | 0.77 | ATM (0.47) | ALDH1A1LMNASMN1; SMN2KMT2AGUSB | |
| SCHEMBL9869659 | 0.74 | CACNA1F (0.45) | ALDH1A1LMNAALOX12KMT2ACACNA1D | |
| SCHEMBL7410687 | 0.73 | CACNA1B (0.61) | ALDH1A1KMT2ACACNA1BUSP2ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5071849-A | Antiinflammatory, antianginal agent | EGIS GYOGYSZERGYAR (HU) | 1991-12-10 | — | — | US | disclosed |