Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9870900 | 0.84 | ATM (0.45) | ATMTSHRALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL9871298 | 0.82 | ATM (0.47) | ATMALDH1A1SMN1; SMN2KDM4EMAPT | |
| SCHEMBL9690101 | 0.78 | KMT2A (0.43) | ATMTSHRALDH1A1KDM4EMAPT | |
| SCHEMBL9870418 | 0.78 | GAA (0.47) | TSHRALDH1A1SMN1; SMN2KDM4EMAPT | |
| SCHEMBL9870211 | 0.77 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2MAPTLMNAKMT2A | |
| SCHEMBL9870854 | 0.76 | ALDH1A1 (0.43) | ATMALDH1A1SMN1; SMN2KDM4EMAPT | |
| SCHEMBL9869833 | 0.73 | CACNA1F (0.42) | ATMALDH1A1MAPTLMNA | |
| SCHEMBL9870706 | 0.70 | ALDH1A1 (0.38) | ALDH1A1SMN1; SMN2KDM4EMAPTGAA | |
| SCHEMBL9871899 | 0.69 | CACNA1F (0.60) | ALDH1A1SMN1; SMN2GAALMNAHPGD | |
| SCHEMBL15247242 | 0.68 | MAPT (0.53) | ALDH1A1KDM4EMAPTGAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5071849-A | Antiinflammatory, antianginal agent | EGIS GYOGYSZERGYAR (HU) | 1991-12-10 | — | — | US | disclosed |