Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 1/20 | 0.47 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | AGER | Q15109 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MYC | P01106 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | DHODH | Q02127 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10592471 | 0.87 | L3MBTL1 (0.49) | HCRTR1HCRTR2KDM4EALDH1A1MAPT | |
| SCHEMBL7842595 | 0.85 | HCRTR1 (0.43) | HCRTR1HCRTR2KDM4EALDH1A1ALOX15 | |
| SCHEMBL7842597 | 0.81 | GAA (0.40) | HCRTR1HCRTR2KDM4EALDH1A1MAPT | |
| SCHEMBL27404062 | 0.81 | ALDH1A1 (0.43) | HCRTR1HCRTR2KDM4EALDH1A1MAPT | |
| SCHEMBL28429986 | 0.78 | — | — | |
| SCHEMBL8810479 | 0.77 | ALDH1A1 (0.53) | HCRTR1HCRTR2KDM4EALDH1A1MAPT | |
| SCHEMBL7814676 | 0.77 | CTSA (0.57) | ALDH1A1CYP3A4NPSR1CYP1A2 | |
| SCHEMBL3390642 | 0.77 | KDM4E (0.59) | KDM4EALDH1A1MAPTCYP3A4ALOX15 | |
| SCHEMBL2405487 | 0.77 | MKNK1 (0.49) | HCRTR1HCRTR2KDM4EALDH1A1MAPT | |
| SCHEMBL9694228 | 0.76 | CTSA (0.56) | ALDH1A1CYP3A4NPSR1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5006155-A | Containing triazine or pyrimidine ring | RHEINHEIMER JOACHIM (DE) | 1991-04-09 | — | — | US | disclosed |