Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | GFER | P55789 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 9/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9871534 | 0.80 | POLB (0.47) | POLBALDH1A1TSHRGFERL3MBTL1 | |
| SCHEMBL9241824 | 0.74 | MAPT (0.54) | POLBALDH1A1TSHRGFERL3MBTL1 | |
| SCHEMBL9240923 | 0.73 | POLB (0.39) | POLBALDH1A1TSHRGFERL3MBTL1 | |
| SCHEMBL9238134 | 0.72 | ATM (0.51) | POLBALDH1A1TSHRGFERL3MBTL1 | |
| SCHEMBL20649419 | 0.70 | POLB (0.46) | POLBALDH1A1TSHRGFERL3MBTL1 | |
| SCHEMBL1735497 | 0.68 | ALDH1A1 (0.74) | ALDH1A1TSHRGFERL3MBTL1CYP3A4 | |
| SCHEMBL9872297 | 0.67 | KMT2A (0.41) | ALDH1A1KMT2AGAARAB9AMAPT | |
| Hydrochloric Acid SCHEMBL8046146 | 0.66 | ALDH1A1 (0.70) | ALDH1A1TSHRGFERL3MBTL1CYP3A4 | |
| Hydrochloric Acid SCHEMBL8046149 | 0.66 | ALDH1A1 (0.70) | ALDH1A1TSHRGFERL3MBTL1CYP3A4 | |
| SCHEMBL1972710 | 0.64 | ALDH1A1 (0.67) | ALDH1A1TSHRGFERL3MBTL1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5019611-A | Tetrahydrotriazinethiones | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1991-05-28 | — | — | US | disclosed |
| EP-0278890-A2 | Non-staining and slightly-staining antiozonants | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1988-08-17 | — | — | EP | disclosed |