Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.35 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
| ▸ | LIPE | Q05469 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9872539 | 0.80 | KMT2A (0.41) | KMT2AALDH1A3MAPTALDH1A1USP2 | |
| SCHEMBL11504237 | 0.69 | KMT2A (0.49) | KMT2AALDH1A3MAPTALDH1A1USP2 | |
| SCHEMBL125543 | 0.68 | ALDH1A3 (0.64) | KMT2AALDH1A3GAAALDH1A1TP53 | |
| SCHEMBL9870477 | 0.67 | POLB (0.50) | KMT2AALDH1A3MAPTGAAALDH1A1 | |
| SCHEMBL20000542 | 0.66 | MAPT (0.66) | KMT2AALDH1A3MAPTGAAALDH1A1 | |
| SCHEMBL25094272 | 0.66 | LIPE (0.53) | KMT2AMAPTALDH1A1USP2ALOX15 | |
| Hydrogen Peroxide SCHEMBL28902806 | 0.64 | KMT2A (0.70) | KMT2AALDH1A3GAAALDH1A1TP53 | |
| SCHEMBL2579648 | 0.63 | HTR3E (0.48) | KMT2AMAPTGAATP53SMN1; SMN2 | |
| SCHEMBL2096252 | 0.63 | ALDH1A3 (0.52) | KMT2AALDH1A3GAAALDH1A1SMN1; SMN2 | |
| SCHEMBL5563 | 0.63 | PARP10 (0.54) | KMT2AALDH1A3MAPTGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5019611-A | Tetrahydrotriazinethiones | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1991-05-28 | — | — | US | disclosed |
| EP-0278890-A2 | Non-staining and slightly-staining antiozonants | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1988-08-17 | — | — | EP | disclosed |