Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRS3 | P32247 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | MMP13 | P45452 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 4/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27663985 | 0.76 | BRS3 (0.57) | BRS3HPGDMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL9784651 | 0.76 | BRS3 (0.64) | BRS3HPGDMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL10578851 | 0.75 | BRS3 (0.74) | BRS3LMNAMAPTSMN1; SMN2SHMT2 | |
| SCHEMBL10715411 | 0.75 | BRS3 (0.68) | BRS3HPGDMAPTSMN1; SMN2ALDH1A1 | |
| Ufiprazole SCHEMBL662986 | 0.75 | BRS3 (0.84) | BRS3LMNAHPGDMAPTSMN1; SMN2 | |
| Ufiprazole SCHEMBL29693729 | 0.75 | BRS3 (1.00) | BRS3HPGDMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL10578102 | 0.75 | BRS3 (0.61) | BRS3HPGDTSHRMAPTSMN1; SMN2 | |
| SCHEMBL10574894 | 0.75 | BRS3 (0.61) | BRS3HPGDTSHRMAPTSMN1; SMN2 | |
| Ufiprazole SCHEMBL29455226 | 0.75 | BRS3 (0.84) | BRS3LMNAHPGDMAPTSMN1; SMN2 | |
| Ufiprazole SCHEMBL1816535 | 0.75 | BRS3 (1.00) | BRS3HPGDMAPTSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5037830-A | Antisecretory-antiulcer agents | RICHTER GEDEON VEGYESZETI GYAR RT (HU) | 1991-08-06 | — | — | US | disclosed |
| EP-0391254-A2 | Novel thiouracil derivatives pharmaceutical compositions containing them and process for preparing same | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 1990-10-10 | — | — | EP | disclosed |