Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.53 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | LTA4H | P09960 | 2/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 2/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.39 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9870647 | 1.00 | MTNR1A (0.53) | MTNR1AMTNR1BLMNALTA4HCA4 | |
| SCHEMBL16254957 | 0.91 | MTNR1A (0.55) | MTNR1AMTNR1BLMNALTA4HKDM4E | |
| SCHEMBL23586068 | 0.89 | MTNR1A (0.46) | MTNR1AMTNR1BLMNALTA4HSLC6A4 | |
| SCHEMBL9770209 | 0.89 | MTNR1A (0.49) | MTNR1AMTNR1BLMNALTA4HCA4 | |
| SCHEMBL14681530 | 0.87 | LMNA (0.53) | MTNR1AMTNR1BLMNALTA4HCYP1A2 | |
| SCHEMBL1142634 | 0.87 | LMNA (0.53) | MTNR1AMTNR1BLMNALTA4HCYP1A2 | |
| SCHEMBL11327496 | 0.87 | LMNA (0.53) | MTNR1AMTNR1BLMNALTA4HCYP1A2 | |
| SCHEMBL14681592 | 0.87 | MTNR1A (0.47) | MTNR1AMTNR1BLMNALTA4HSLC6A4 | |
| SCHEMBL14681486 | 0.87 | MTNR1A (0.47) | MTNR1AMTNR1BLMNALTA4HSLC6A4 | |
| SCHEMBL9870750 | 0.87 | CYP1A2 (0.56) | MTNR1AMTNR1BMAOACYP1A2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5043094-A | Optically active bisaryl compound | ADEKA ARGUS CHEMICAL CO., LTD. (JP) | 1991-08-27 | — | — | US | claimed |
| JP-1258635-A | — | — | None | — | — | JP | disclosed |
| US-5043094-A | Optically active bisaryl compound | ADEKA ARGUS CHEMICAL CO., LTD. (JP) | 1991-08-27 | — | — | US | disclosed |
| JP-H01258635-A | OPTICALLY ACTIVE BISARYL COMPOUND | ADEKA ARGUS CHEM CO LTD | 1989-10-16 | — | — | JP | disclosed |