Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | NPY5R | Q15761 | 16/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CTSK | P43235 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21904916 | 0.83 | POLB (0.71) | POLBNPY5RKMT2A | |
| SCHEMBL9871568 | 0.78 | POLB (0.60) | POLBNPY5RKMT2A | |
| SCHEMBL9870858 | 0.78 | POLB (0.65) | POLBNPY5RKMT2ACTSK | |
| SCHEMBL9871019 | 0.77 | POLB (0.57) | POLBNPY5RALDH1A1KMT2A | |
| SCHEMBL5759619 | 0.73 | MEN1 (0.61) | ALDH1A1KMT2A | |
| SCHEMBL9525617 | 0.73 | POLB (0.71) | POLBNPY5RKMT2A | |
| SCHEMBL9184563 | 0.72 | POLB (1.00) | POLBNPY5RKMT2A | |
| SCHEMBL9879206 | 0.71 | POLB (0.80) | POLBNPY5RKMT2A | |
| SCHEMBL21904831 | 0.71 | POLB (0.52) | POLBNPY5R | |
| SCHEMBL9594529 | 0.71 | POLB (0.67) | POLBNPY5RKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5059599-A | Anxiolytic agents | PIERRE FABRE MEDICAMENT (FR) | 1991-10-22 | — | — | US | disclosed |