Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 3/20 | 0.40 |
| ▸ | CA12 | O43570 | 3/20 | 0.38 |
| ▸ | CA1 | P00915 | 3/20 | 0.38 |
| ▸ | CA2 | P00918 | 3/20 | 0.38 |
| ▸ | CA9 | Q16790 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | DGKA | P23743 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.32 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.32 |
| ▸ | NAAA | Q02083 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9869684 | 1.00 | ACHE (0.40) | ACHECA12CA1CA2CA9 | |
| SCHEMBL9874541 | 1.00 | ACHE (0.40) | ACHECA12CA1CA2CA9 | |
| SCHEMBL9870711 | 0.93 | ALDH1A1 (0.39) | ACHECA12CA1CA2CA9 | |
| SCHEMBL9870493 | 0.91 | ALDH1A1 (0.38) | ACHECA12CA1CA2CA9 | |
| SCHEMBL11171248 | 0.85 | CA12 (0.52) | ACHECA12CA1CA2CA9 | |
| SCHEMBL9870541 | 0.85 | ALDH1A1 (0.42) | ALDH1A1TSHRTHRBCYP2D6 | |
| SCHEMBL20817910 | 0.85 | CA12 (0.52) | ACHECA12CA1CA2CA9 | |
| SCHEMBL9871145 | 0.84 | ACHE (0.41) | ACHECA12CA1CA2CA9 | |
| SCHEMBL9869673 | 0.84 | CA12 (0.41) | ACHECA12CA1CA2CA9 | |
| SCHEMBL19376330 | 0.84 | CA12 (0.50) | ACHECA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5026492-A | Synergistic; improved wear resistance in internal combustion engines | EXXON RESEARCH & ENGINEERING COMPANY (US) | 1991-06-25 | — | — | US | disclosed |