Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.34 |
| ▸ | MAOA | P21397 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9871274 | 0.80 | LMNA (0.34) | GAAKMT2ACYP1A2CYP2D6CYP2C9 | |
| Hydrochloric Acid SCHEMBL9870486 | 0.73 | CYP1A2 (0.35) | GAACYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL9870554 | 0.72 | GAA (0.31) | GAACYP1A2CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL9820749 | 0.67 | — | — | |
| SCHEMBL9820704 | 0.67 | CYP1A2 (0.33) | CYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL9820734 | 0.66 | CYP1A2 (0.34) | CYP1A2CYP2D6CYP2C9CYP2C19 | |
| Hydrochloric Acid SCHEMBL9872263 | 0.66 | CYP1A2 (0.32) | CYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL9820707 | 0.65 | CYP1A2 (0.37) | GAAKMT2ACYP1A2CYP2D6CYP2C9 | |
| SCHEMBL9820890 | 0.65 | ALDH1A1 (0.31) | GAAKMT2ANPC1ALDH1A1RAB9A | |
| Hydrochloric Acid SCHEMBL9870033 | 0.63 | GLB1 (0.36) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5017724-A | Antihypoxic, CNS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1991-05-21 | — | — | US | disclosed |
| EP-0267024-A2 | Hydrofluorene derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1988-05-11 | — | — | EP | disclosed |