SCHEMBL987089

SCHEMBL987089

CCCC(NC)c1ccc2c(c1)OOC2

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5493121 0.81 PDE4D (0.40)
SCHEMBL5487522 0.77 PDE4D (0.39)
SCHEMBL23069137 0.76 HTR1B (0.37)
SCHEMBL987091 0.76 MEN1 (0.49)
SCHEMBL70197 0.74 LMNA (0.35)
SCHEMBL1740905 0.70 HTR1B (0.48)
SCHEMBL23069122 0.70 SLC6A4 (0.36)
SCHEMBL15902430 0.69 TAAR1 (0.57)
SCHEMBL11693561 0.69 PDE4D (0.40)
SCHEMBL3526218 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7901949-B2 Assay ALERE SWITZERLAND GMBH (CH) 2011-03-08 US claimed
EP-1701949-B1 ASSAY FOR ENTACTOGENS SIEMENS HEALTHCARE DIAGNOSTICS INC (US) 2018-04-18 EP disclosed
EP-2382458-B1 A CONDUCTIVITY MEASUREMENT CELL SPD SWISS PREC DIAGNOSTICS GMBH (CH) 2018-02-21 EP disclosed
US-9689821-B2 Conductivity measurement cell SPD SWISS PRECISION DIAGNOSTICS GMBH (CH) 2017-06-27 US disclosed
US-9151749-B2 Assay device comprising bubble-forming means ALERE SWITZERLAND GMBH (CH) 2015-10-06 US disclosed
EP-2269067-B1 ASSAY DEVICE COMPRISING BUBBLE-FORMING MEANS SPD SWISS PREC DIAGNOSTICS GMBH (CH) 2015-02-25 EP disclosed
EP-1828106-B1 METHAMPHETAMINE DERIVATIVES AND CONJUGATES FOR IMMUNOASSAY ROCHE DIAGNOSTICS GMBH (DE) 2012-10-31 EP disclosed
EP-2382458-A2 A CONDUCTIVITY MEASUREMENT CELL SPD Swiss Precision Diagnostics Gmbh (CH) 2011-11-02 EP disclosed
US-20110223690-A1 ASSAY RAJ BALBIR 2011-09-15 US disclosed
EP-2269067-A1 ASSAY DEVICE COMPRISING BUBBLE-FORMING MEANS SPD Swiss Precision Diagnostics Gmbh (CH) 2011-01-05 EP disclosed
US-7101980-B2 Derivatives, conjugates, and antibodies for detecting ecstasy-class analytes ROCHE DIAGNOSTICS OPERATIONS, INC. (US) 2006-09-05 US disclosed
US-20060134711-A1 Methamphetamine derivatives and conjugates for immunoassay ROCHE DIAGNOSTICS OPERATIONS, INC. 2006-06-22 US disclosed
WO-2006063829-A2 METHAMPHETAMINE DERIVATIVES AND CONJUGATES FOR IMMUNOASSAY ROCHE DIAGNOSTICS GMBH (DE) 2006-06-22 WO disclosed
WO-2005059547-A2 ASSAY INVERNESS MEDICAL SWITZERLAND GMBH (CH) 2005-06-30 WO disclosed
EP-1498428-A1 Antibodies for detecting ecstasy-class analytes Roche Diagnostics GmbH (DE) 2005-01-19 EP disclosed
US-20040077021-A1 Derivatives, conjugates, and antibodies for detecting ecstasy-class analytes ROCHE DIAGNOSTICS CORPORATION 2004-04-22 US disclosed
US-20030175995-A1 Compounds, antibodies, reagent kits, methods of producing antibodies, and methods of detecting analytes ROCHE DIAGNOSTICS OPERATIONS, INC. 2003-09-18 US disclosed
US-20030170917-A1 Compounds, antibodies, reagent kits, methods of producing antibodies, and methods of detecting analytes ROCHE DIAGNOSTICS CORPORATION 2003-09-11 US disclosed
EP-1340981-A2 Antibodies for detecting amphetamine derivatives Roche Diagnostics GmbH (DE) 2003-09-03 EP disclosed
EP-1340980-A1 Derivatives of amphetamine, antibodies against said derivatives, reagent kits, methods of producing said antibodies, and methods of detecting said derivatives Roche Diagnostics GmbH (DE) 2003-09-03 EP disclosed