Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | TAS1R3 | Q7RTX0 | 4/20 | 0.48 |
| ▸ | TAS1R1 | Q7RTX1 | 4/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29391939 | 0.87 | CYP2D6 (0.50) | MEN1KMT2AKDM4ECYP2D6SLC6A2 | |
| SCHEMBL6128678 | 0.86 | CYP2D6 (0.47) | MEN1KMT2AKDM4ECYP2D6SLC6A2 | |
| Hydrochloric Acid SCHEMBL30496130 | 0.86 | CYP2D6 (0.49) | MEN1KMT2AKDM4ECYP2D6SLC6A2 | |
| SCHEMBL11630599 | 0.83 | TAAR1 (0.49) | MEN1KMT2AKDM4ECYP2D6SLC6A2 | |
| SCHEMBL9271139 | 0.80 | TAS1R3 (0.52) | MEN1KMT2ATAS1R3TAS1R1HPGD | |
| SCHEMBL5457069 | 0.80 | RAB9A (0.47) | MEN1KMT2AKDM4ETAS1R3TAS1R1 | |
| SCHEMBL5493126 | 0.79 | AOC3 (0.53) | MEN1KMT2AKDM4ETAS1R3TAS1R1 | |
| SCHEMBL22854153 | 0.79 | MEN1 (0.52) | MEN1KMT2AKDM4ETAS1R3TAS1R1 | |
| SCHEMBL8712770 | 0.79 | AOC3 (0.53) | MEN1KMT2AKDM4ETAS1R3TAS1R1 | |
| SCHEMBL20976479 | 0.78 | KMT2A (0.59) | KMT2ACYP1A2CYP2C9CYP2C19HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7901949-B2 | Assay | ALERE SWITZERLAND GMBH (CH) | 2011-03-08 | — | — | US | claimed |
| CN-112156497-B | Liquid-liquid electro-extraction device for enriching trace analytes and capable of realizing two phases of non-aqueous mutual solution and application of liquid-liquid electro-extraction device | 南方医科大学 | 2021-10-12 | — | — | CN | disclosed |
| CN-112156497-A | Liquid-liquid electro-extraction device for enriching trace analytes and capable of realizing two phases of non-aqueous mutual solution and application of liquid-liquid electro-extraction device | 南方医科大学 | 2021-01-01 | — | — | CN | disclosed |
| EP-1701949-B1 | ASSAY FOR ENTACTOGENS | SIEMENS HEALTHCARE DIAGNOSTICS INC (US) | 2018-04-18 | — | — | EP | disclosed |
| EP-2382458-B1 | A CONDUCTIVITY MEASUREMENT CELL | SPD SWISS PREC DIAGNOSTICS GMBH (CH) | 2018-02-21 | — | — | EP | disclosed |
| US-9689821-B2 | Conductivity measurement cell | SPD SWISS PRECISION DIAGNOSTICS GMBH (CH) | 2017-06-27 | — | — | US | disclosed |
| US-9151749-B2 | Assay device comprising bubble-forming means | ALERE SWITZERLAND GMBH (CH) | 2015-10-06 | — | — | US | disclosed |
| EP-2269067-B1 | ASSAY DEVICE COMPRISING BUBBLE-FORMING MEANS | SPD SWISS PREC DIAGNOSTICS GMBH (CH) | 2015-02-25 | — | — | EP | disclosed |
| EP-1828106-B1 | METHAMPHETAMINE DERIVATIVES AND CONJUGATES FOR IMMUNOASSAY | ROCHE DIAGNOSTICS GMBH (DE) | 2012-10-31 | — | — | EP | disclosed |
| EP-2382458-A2 | A CONDUCTIVITY MEASUREMENT CELL | SPD Swiss Precision Diagnostics Gmbh (CH) | 2011-11-02 | — | — | EP | disclosed |
| US-7101980-B2 | Derivatives, conjugates, and antibodies for detecting ecstasy-class analytes | ROCHE DIAGNOSTICS OPERATIONS, INC. (US) | 2006-09-05 | — | — | US | disclosed |
| US-20060134711-A1 | Methamphetamine derivatives and conjugates for immunoassay | ROCHE DIAGNOSTICS OPERATIONS, INC. | 2006-06-22 | — | — | US | disclosed |
| WO-2006063829-A2 | METHAMPHETAMINE DERIVATIVES AND CONJUGATES FOR IMMUNOASSAY | ROCHE DIAGNOSTICS GMBH (DE) | 2006-06-22 | — | — | WO | disclosed |
| WO-2005059547-A2 | ASSAY | INVERNESS MEDICAL SWITZERLAND GMBH (CH) | 2005-06-30 | — | — | WO | disclosed |
| EP-1498428-A1 | Antibodies for detecting ecstasy-class analytes | Roche Diagnostics GmbH (DE) | 2005-01-19 | — | — | EP | disclosed |
| US-20040077021-A1 | Derivatives, conjugates, and antibodies for detecting ecstasy-class analytes | ROCHE DIAGNOSTICS CORPORATION | 2004-04-22 | — | — | US | disclosed |
| US-20030175995-A1 | Compounds, antibodies, reagent kits, methods of producing antibodies, and methods of detecting analytes | ROCHE DIAGNOSTICS OPERATIONS, INC. | 2003-09-18 | — | — | US | disclosed |
| US-20030170917-A1 | Compounds, antibodies, reagent kits, methods of producing antibodies, and methods of detecting analytes | ROCHE DIAGNOSTICS CORPORATION | 2003-09-11 | — | — | US | disclosed |
| EP-1340981-A2 | Antibodies for detecting amphetamine derivatives | Roche Diagnostics GmbH (DE) | 2003-09-03 | — | — | EP | disclosed |
| EP-1340980-A1 | Derivatives of amphetamine, antibodies against said derivatives, reagent kits, methods of producing said antibodies, and methods of detecting said derivatives | Roche Diagnostics GmbH (DE) | 2003-09-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060134711-A1 | Methamphetamine derivatives and conjugates for immunoassay | PNMT, COMT, MCHR1 | MEN1 206/4885KMT2A 382/4885KDM4E 1180/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.