Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 2/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.34 |
| ▸ | LDLR | P01130 | 1/20 | 0.34 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.33 |
| ▸ | CXCR4 | P61073 | 2/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 6/20 | 0.32 |
| ▸ | NPC1 | O15118 | 4/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.31 |
| ▸ | KIF11 | P52732 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12490702 | 0.70 | TRPM8 (0.35) | HDAC1EPHX2ALDH1A1HDAC8KIF11 | |
| Cyclohexanol SCHEMBL10392947 | 0.68 | EPHX2 (0.46) | EPHX2RAB9ANPC1ALDH1A1HPGD | |
| SCHEMBL16499616 | 0.66 | DAO (0.45) | LDLREPHX2 | |
| SCHEMBL12490205 | 0.66 | KIF11 (0.36) | EPHX2KIF11DDB1CRBN | |
| SCHEMBL1692149 | 0.65 | HAO1 (0.46) | HDAC1HDAC6HRH3ALDH1A1HDAC8 | |
| SCHEMBL15102171 | 0.65 | LCK (0.41) | HRH3RAB9ANPC1ALDH1A1SMN1; SMN2 | |
| Formic Acid SCHEMBL11392898 | 0.64 | TSHR (0.50) | HDAC8HPGD | |
| SCHEMBL18030797 | 0.63 | DAO (0.42) | LDLR | |
| SCHEMBL18843593 | 0.63 | MEN1 (0.49) | HRH3RAB9ANPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL7443737 | 0.63 | NPC1 (0.66) | HDAC1RAB9ANPC1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4988707-A | Platelet activating factor, antiinflammatory agents, cardiovascular disorders and treatment of asthma | G. D. SEARLE & CO. (US) | 1991-01-29 | — | — | US | disclosed |