Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9872560 | 0.77 | SLC6A2 (0.33) | MEN1KMT2AMAOBALDH1A1CYP1A2 | |
| SCHEMBL29299973 | 0.65 | MEN1 (0.57) | MEN1KMT2ALMNAADORA3GAA | |
| SCHEMBL29299975 | 0.65 | MEN1 (0.57) | MEN1KMT2ALMNAADORA3GAA | |
| SCHEMBL15676298 | 0.60 | GRM5 (0.44) | MEN1KMT2ALMNAADORA3CYP2D6 | |
| SCHEMBL19061962 | 0.60 | GRM5 (0.44) | MEN1KMT2ALMNAADORA3CYP2D6 | |
| SCHEMBL15699098 | 0.60 | GRM5 (0.44) | MEN1KMT2ALMNAADORA3CYP2D6 | |
| SCHEMBL19795866 | 0.60 | GRM5 (0.44) | MEN1KMT2ALMNAADORA3CYP2D6 | |
| SCHEMBL8977802 | 0.58 | ALDH1A1 (0.47) | MEN1KMT2AALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL11573778 | 0.57 | TSHR (0.39) | LMNAMAOBMAPK1CYP1A2CYP3A4 | |
| SCHEMBL18287177 | 0.57 | MEN1 (0.33) | MEN1KMT2ALMNAMAOBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-58157793-A | — | — | None | — | — | JP | disclosed |
| US-4996208-A | Pesticidal thiazolopyrimidine derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 1991-02-26 | — | — | US | disclosed |
| EP-0348746-A2 | Thiazolopyrimidine derivatives, process for their preparation and their use as pest control agents | BAYER AG (DE) | 1990-01-03 | — | — | EP | disclosed |
| JP-S58157793-A | THIAZOLINOTRIAZINE DERIVATIVE AND AGRICULTURAL AND HORTICULTURAL FUNGICIDE | NIPPON SODA CO LTD | 1983-09-19 | — | — | JP | disclosed |