Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8977802 | 0.77 | ALDH1A1 (0.47) | SLC6A2ADRA1AHTR2BSLC6A3ALDH1A1 | |
| SCHEMBL9870950 | 0.77 | MEN1 (0.38) | ALDH1A1HPGDCYP1A2CYP2D6CYP2C19 | |
| SCHEMBL9635178 | 0.69 | TNKS2 (0.42) | ALDH1A1HPGDHSD17B10TSHRKDM4E | |
| SCHEMBL8188471 | 0.63 | GLA (0.33) | HTR2BHPGDTSHRKDM4ECHRNA7 | |
| SCHEMBL11573778 | 0.61 | TSHR (0.39) | SLC6A2ADRA1AHTR2BSLC6A3CYP1A2 | |
| SCHEMBL29025323 | 0.60 | SLC6A2 (0.47) | SLC6A2ADRA1AHTR2BSLC6A3ALDH1A1 | |
| SCHEMBL27686420 | 0.60 | TSHR (0.42) | ALDH1A1HPGDHSD17B10TSHRMEN1 | |
| SCHEMBL23465393 | 0.60 | CHRNA7 (0.54) | SLC6A2ADRA1AHTR2BSLC6A3ALDH1A1 | |
| SCHEMBL18244886 | 0.60 | CHRNA7 (0.54) | SLC6A2ADRA1AHTR2BSLC6A3ALDH1A1 | |
| SCHEMBL18360030 | 0.60 | CHRNA7 (0.54) | SLC6A2ADRA1AHTR2BSLC6A3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4996208-A | Pesticidal thiazolopyrimidine derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 1991-02-26 | — | — | US | disclosed |
| EP-0348746-A2 | Thiazolopyrimidine derivatives, process for their preparation and their use as pest control agents | BAYER AG (DE) | 1990-01-03 | — | — | EP | disclosed |