Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9871150 | 0.83 | ALDH1A1 (0.45) | ALDH1A1CYP3A4ALOX15TSHRHIF1A | |
| SCHEMBL9238458 | 0.75 | ATM (0.45) | ALDH1A1CYP3A4ALOX15TSHRHIF1A | |
| SCHEMBL144947 | 0.74 | ALDH1A1 (0.73) | ALDH1A1CYP3A4ALOX15TSHRHIF1A | |
| SCHEMBL1417898 | 0.69 | ALDH1A1 (0.61) | ALDH1A1CYP3A4ALOX15TSHRHIF1A | |
| SCHEMBL9933293 | 0.69 | ALDH1A1 (0.85) | ALDH1A1CYP3A4ALOX15TSHRHIF1A | |
| SCHEMBL9872297 | 0.68 | KMT2A (0.41) | ALDH1A1ALOX15HSD17B10TP53SMN1; SMN2 | |
| SCHEMBL9238414 | 0.68 | ALDH1A1 (0.47) | ALDH1A1CYP3A4ALOX15TSHRHIF1A | |
| SCHEMBL24564966 | 0.67 | ALDH1A1 (0.63) | ALDH1A1CYP3A4ALOX15TSHRHIF1A | |
| SCHEMBL9511506 | 0.67 | ALDH1A1 (0.63) | ALDH1A1CYP3A4ALOX15TSHRHIF1A | |
| SCHEMBL13996001 | 0.67 | ALDH1A1 (0.63) | ALDH1A1CYP3A4ALOX15TSHRHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5019611-A | Tetrahydrotriazinethiones | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1991-05-28 | — | — | US | disclosed |
| EP-0278890-A2 | Non-staining and slightly-staining antiozonants | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1988-08-17 | — | — | EP | disclosed |