Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.66 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.66 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.62 |
| ▸ | HPGD | P15428 | 3/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | MAOB | P27338 | 2/20 | 0.49 |
| ▸ | ACHE | P22303 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9872622 | 0.94 | RAB9A (0.62) | RAB9AKMT2ATDP1L3MBTL1HPGD | |
| SCHEMBL9871929 | 0.93 | RAB9A (0.57) | RAB9AKMT2ATDP1L3MBTL1MAPT | |
| SCHEMBL9871761 | 0.88 | RAB9A (0.63) | RAB9AKMT2ATDP1L3MBTL1HPGD | |
| SCHEMBL9872136 | 0.85 | RAB9A (0.60) | RAB9AKMT2ATDP1L3MBTL1HPGD | |
| SCHEMBL10488542 | 0.85 | RAB9A (0.71) | RAB9AKMT2ATDP1L3MBTL1HPGD | |
| Dimethylamine SCHEMBL9871769 | 0.82 | RAB9A (0.66) | RAB9AKMT2ATDP1L3MBTL1HPGD | |
| SCHEMBL9871916 | 0.81 | RAB9A (0.59) | RAB9AKMT2ATDP1L3MBTL1HPGD | |
| SCHEMBL9872868 | 0.81 | RAB9A (0.58) | RAB9AKMT2ATDP1L3MBTL1HPGD | |
| SCHEMBL9871968 | 0.81 | RAB9A (0.54) | RAB9AKMT2ATDP1L3MBTL1MAPT | |
| SCHEMBL2206888 | 0.80 | RAB9A (0.67) | RAB9AKMT2ATDP1L3MBTL1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5021429-A | Histamine h2-antagonists; antisecretory-antiallergen agent; skin disorders and peptic ulcers | ALLEN & HANSBURYS LIMITED (GB) | 1991-06-04 | — | — | US | disclosed |