Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.62 |
| ▸ | MAPT | P10636 | 3/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | MAOB | P27338 | 3/20 | 0.52 |
| ▸ | ACHE | P22303 | 9/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9871929 | 0.96 | RAB9A (0.57) | RAB9AMAPTSMN1; SMN2KMT2ATDP1 | |
| SCHEMBL9871029 | 0.94 | RAB9A (0.66) | RAB9AMAPTSMN1; SMN2KMT2ATDP1 | |
| SCHEMBL9871916 | 0.88 | RAB9A (0.59) | RAB9AMAPTSMN1; SMN2KMT2ATDP1 | |
| SCHEMBL9872868 | 0.87 | RAB9A (0.58) | RAB9AMAPTSMN1; SMN2KMT2ATDP1 | |
| SCHEMBL9871968 | 0.84 | RAB9A (0.54) | RAB9AMAPTSMN1; SMN2KMT2ATDP1 | |
| SCHEMBL9871275 | 0.83 | RAB9A (0.53) | RAB9AMAPTSMN1; SMN2KMT2ATDP1 | |
| SCHEMBL11178851 | 0.83 | RAB9A (0.67) | RAB9AMAPTSMN1; SMN2KMT2ATDP1 | |
| SCHEMBL9860255 | 0.83 | RAB9A (0.67) | RAB9AMAPTSMN1; SMN2KMT2ATDP1 | |
| SCHEMBL18732030 | 0.82 | RAB9A (0.62) | RAB9AMAPTSMN1; SMN2KMT2ATDP1 | |
| Dimethylamine SCHEMBL9871927 | 0.82 | MAPT (0.62) | RAB9AMAPTSMN1; SMN2KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5021429-A | Histamine h2-antagonists; antisecretory-antiallergen agent; skin disorders and peptic ulcers | ALLEN & HANSBURYS LIMITED (GB) | 1991-06-04 | — | — | US | disclosed |