Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPRT1 | P00492 | 8/20 | 0.44 |
| ▸ | NOS1 | P29475 | 5/20 | 0.33 |
| ▸ | PNP | P00491 | 1/20 | 0.32 |
| ▸ | NOS3 | P29474 | 1/20 | 0.31 |
| ▸ | NOS2 | P35228 | 1/20 | 0.31 |
| ▸ | TK1 | P04183 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | CASP7 | P55210 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | PAH | P00439 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9470564 | 0.85 | HPRT1 (0.44) | HPRT1NOS1NOS3NOS2CYP1A2 | |
| SCHEMBL9665218 | 0.75 | HPRT1 (0.40) | HPRT1NOS1PNPTK1USP2 | |
| SCHEMBL9739844 | 0.74 | HPRT1 (0.60) | HPRT1NOS1PNPNOS3NOS2 | |
| SCHEMBL3836268 | 0.72 | HPRT1 (0.61) | HPRT1NOS1PNPNOS3NOS2 | |
| SCHEMBL9310753 | 0.71 | HPRT1 (0.46) | HPRT1NOS1NOS3NOS2USP2 | |
| SCHEMBL571646 | 0.71 | HPRT1 (0.60) | HPRT1NOS1PNPTK1CYP1A2 | |
| SCHEMBL7765227 | 0.70 | HPRT1 (0.47) | HPRT1NOS1NOS3NOS2TK1 | |
| SCHEMBL4242270 | 0.70 | HPRT1 (0.50) | HPRT1NOS1PNPTK1USP2 | |
| SCHEMBL10917986 | 0.69 | HPRT1 (0.52) | HPRT1NOS1PNPNOS3NOS2 | |
| SCHEMBL146427 | 0.69 | HPRT1 (0.61) | HPRT1PNPUSP2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4988703-A | Viricides of hydroxyethylcyclopropylguanine | ABBOTT LABORATORIES (US) | 1991-01-29 | — | — | US | disclosed |