Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.55 |
| ▸ | PTPRB | P23467 | 1/20 | 0.53 |
| ▸ | CDC25A | P30304 | 1/20 | 0.53 |
| ▸ | CDC25B | P30305 | 1/20 | 0.53 |
| ▸ | PTEN | P60484 | 1/20 | 0.53 |
| ▸ | PTPMT1 | Q8WUK0 | 1/20 | 0.53 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.52 |
| ▸ | PPARG | P37231 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.46 |
| ▸ | NOS1 | P29475 | 1/20 | 0.45 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL70271 | 0.85 | KEAP1 (0.74) | KEAP1PTPRBCDC25ACDC25BPTEN | |
| SCHEMBL14558114 | 0.84 | KEAP1 (0.49) | KEAP1PTPRBCDC25ACDC25BPTEN | |
| Hydrochloric Acid SCHEMBL10982620 | 0.83 | KEAP1 (0.71) | KEAP1PTPRBCDC25ACDC25BPTEN | |
| SCHEMBL26211894 | 0.82 | TSHR (0.52) | ALDH1A1TSHRKMT2ANOS1 | |
| SCHEMBL14610940 | 0.82 | FFAR1 (0.59) | KEAP1FFAR1PPARGALDH1A1TSHR | |
| SCHEMBL14569700 | 0.82 | KEAP1 (0.46) | KEAP1PTPRBCDC25ACDC25BPTEN | |
| SCHEMBL3242805 | 0.80 | KEAP1 (0.61) | KEAP1PTPRBCDC25ACDC25BPTEN | |
| SCHEMBL1206832 | 0.80 | KEAP1 (0.61) | KEAP1PTPRBCDC25ACDC25BPTEN | |
| SCHEMBL3674500 | 0.80 | KEAP1 (0.61) | KEAP1PTPRBCDC25ACDC25BPTEN | |
| SCHEMBL10750679 | 0.80 | NOS1 (0.50) | ALDH1A1TSHRNOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7179819-B2 | VLA-4 inhibitor compounds | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2007-02-20 | — | — | US | disclosed |
| US-5021429-A | Histamine h2-antagonists; antisecretory-antiallergen agent; skin disorders and peptic ulcers | ALLEN & HANSBURYS LIMITED (GB) | 1991-06-04 | — | — | US | disclosed |