Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.62 |
| ▸ | THRA | P10827 | 1/20 | 0.58 |
| ▸ | THRB | P10828 | 1/20 | 0.58 |
| ▸ | FFAR1 | O14842 | 6/20 | 0.57 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.55 |
| ▸ | PTPRB | P23467 | 1/20 | 0.53 |
| ▸ | CDC25A | P30304 | 1/20 | 0.53 |
| ▸ | CDC25B | P30305 | 1/20 | 0.53 |
| ▸ | PTEN | P60484 | 1/20 | 0.53 |
| ▸ | PTPMT1 | Q8WUK0 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.49 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL456436 | 0.95 | FFAR4 (0.67) | FFAR4THRATHRBFFAR1KEAP1 | |
| SCHEMBL7507667 | 0.85 | MMP12 (0.54) | FFAR4THRATHRBFFAR1MEN1 | |
| SCHEMBL13525204 | 0.85 | FFAR1 (0.71) | FFAR4THRATHRBFFAR1KEAP1 | |
| Phenyl Propionic Acid SCHEMBL28551157 | 0.85 | FFAR4 (0.57) | FFAR4THRATHRBFFAR1KEAP1 | |
| SCHEMBL5101251 | 0.84 | HDAC3 (0.63) | FFAR4THRATHRBFFAR1KDM4E | |
| SCHEMBL14724832 | 0.83 | MEN1 (0.53) | FFAR4FFAR1MEN1KMT2AKDM4E | |
| SCHEMBL3249491 | 0.83 | MAPT (0.62) | FFAR4THRATHRBFFAR1HDAC3 | |
| SCHEMBL3213481 | 0.82 | HDAC3 (0.52) | FFAR4THRATHRBFFAR1MEN1 | |
| SCHEMBL7337631 | 0.82 | TAAR1 (0.57) | FFAR4THRATHRBFFAR1MEN1 | |
| SCHEMBL765851 | 0.81 | MAPT (0.66) | FFAR4HDAC3HDAC1HDAC2HDAC10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5021429-A | Histamine h2-antagonists; antisecretory-antiallergen agent; skin disorders and peptic ulcers | ALLEN & HANSBURYS LIMITED (GB) | 1991-06-04 | — | — | US | disclosed |