Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.64 |
| ▸ | TOP1 | P11387 | 4/20 | 0.62 |
| ▸ | TOP2A | P11388 | 3/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | HPGD | P15428 | 4/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.54 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.54 |
| ▸ | ALB | P02768 | 1/20 | 0.53 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.53 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.52 |
| ▸ | TUBB | P07437 | 1/20 | 0.52 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.52 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9870380 | 0.92 | KDM4E (0.64) | KDM4ETOP1TOP2AKMT2AMEN1 | |
| SCHEMBL10629481 | 0.91 | KDM4E (0.63) | KDM4ETOP1TOP2AKMT2AMEN1 | |
| SCHEMBL9870883 | 0.89 | TOP2A (0.61) | KDM4ETOP1TOP2AKMT2AMEN1 | |
| SCHEMBL9188127 | 0.89 | KMT2A (0.58) | KDM4ETOP1TOP2AKMT2AMEN1 | |
| SCHEMBL10914229 | 0.88 | KDM4E (0.52) | KDM4ETOP1TOP2AKMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL9773694 | 0.88 | TOP1 (0.56) | KDM4ETOP1TOP2AKMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL9773692 | 0.88 | TOP1 (0.56) | KDM4ETOP1TOP2AKMT2AMEN1 | |
| SCHEMBL9869685 | 0.88 | LMNA (0.68) | KDM4ETOP1TOP2AKMT2AMEN1 | |
| SCHEMBL10635665 | 0.88 | KDM4E (0.59) | KDM4ETOP1TOP2AKMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL9690870 | 0.87 | KDM4E (0.49) | KDM4ETOP1TOP2AKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0201829-A1 | 1-Aryl-4-quinolone-3-carboxylic acids | BAYER AG (DE) | 1986-11-20 | — | — | EP | claimed |
| US-4981854-A | BACTERICIDES, ANIMAL GROWTH REGUALTORS | BAYER AKTIENGESELLSCHAFT (DE) | 1991-01-01 | — | — | US | disclosed |
| US-4980353-A | BACTERICIDES, ANIMAL GROWTH REGULATORS | BAYER AKTIENGESELLSCHAFT (DE) | 1990-12-25 | — | — | US | disclosed |
| EP-0201829-A1 | 1-Aryl-4-quinolone-3-carboxylic acids | BAYER AG (DE) | 1986-11-20 | — | — | EP | disclosed |