Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 10/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.50 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | HTR1A | P08908 | 6/20 | 0.48 |
| ▸ | HTR7 | P34969 | 6/20 | 0.48 |
| ▸ | HTR1D | P28221 | 4/20 | 0.48 |
| ▸ | HTR1B | P28222 | 4/20 | 0.48 |
| ▸ | HTR2A | P28223 | 4/20 | 0.48 |
| ▸ | HTR2B | P41595 | 4/20 | 0.48 |
| ▸ | HTR5A | P47898 | 2/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9872690 | 0.83 | CYP3A4 (0.41) | ALDH1A1HTR2BKCNH2 | |
| SCHEMBL9870672 | 0.82 | HDAC1 (0.42) | ALDH1A1HTR2BKCNH2 | |
| SCHEMBL9872923 | 0.81 | KCNH2 (0.40) | ALDH1A1HTR2BKCNH2 | |
| SCHEMBL9871477 | 0.80 | ALDH1A1 (0.42) | ALDH1A1SMN1; SMN2HTR7HTR2BKCNH2 | |
| SCHEMBL9872568 | 0.77 | CHRNA7 (0.43) | HTR2CALDH1A1MAPT | |
| SCHEMBL9871319 | 0.77 | CHRNA7 (0.44) | ALDH1A1MAPT | |
| SCHEMBL9871678 | 0.75 | SIGMAR1 (0.44) | HTR2CALDH1A1HTR2AHTR2BKCNH2 | |
| Hydrochloric Acid SCHEMBL9871398 | 0.73 | KCNH2 (0.39) | ALDH1A1HTR2BKCNH2 | |
| SCHEMBL9871149 | 0.72 | CYP3A4 (0.38) | ALDH1A1HTR2BKCNH2 | |
| Hydrochloric Acid SCHEMBL9872164 | 0.71 | METAP1 (0.39) | ALDH1A1HTR2BKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5030646-A | Treatment of diseases resulting from disfunction of seretoninergic system | ADIR ET COMPAGNIE (FR) | 1991-07-09 | — | — | US | disclosed |