Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | HEXA | P06865 | 1/20 | 0.44 |
| ▸ | HEXB | P07686 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dimethylamine SCHEMBL9872874 | 0.96 | RAB9A (0.59) | RAB9AMAPTSMN1; SMN2TDP1KMT2A | |
| Dimethylamine SCHEMBL9872141 | 0.93 | RAB9A (0.63) | RAB9AMAPTSMN1; SMN2TDP1KMT2A | |
| Dimethylamine SCHEMBL9871972 | 0.91 | RAB9A (0.57) | RAB9AMAPTSMN1; SMN2TDP1KMT2A | |
| SCHEMBL2202509 | 0.88 | RAB9A (0.57) | RAB9AMAPTSMN1; SMN2TDP1KMT2A | |
| Dimethylamine SCHEMBL9871927 | 0.87 | MAPT (0.62) | RAB9AMAPTSMN1; SMN2TDP1KMT2A | |
| SCHEMBL9871968 | 0.84 | RAB9A (0.54) | RAB9AMAPTSMN1; SMN2TDP1KMT2A | |
| SCHEMBL2210372 | 0.83 | RAB9A (0.57) | RAB9AMAPTSMN1; SMN2TDP1KMT2A | |
| SCHEMBL2206692 | 0.83 | RAB9A (0.57) | RAB9AMAPTSMN1; SMN2TDP1KMT2A | |
| Dimethylamine SCHEMBL9871932 | 0.83 | RAB9A (0.78) | RAB9AMAPTSMN1; SMN2TDP1KMT2A | |
| Dimethylamine SCHEMBL9871769 | 0.83 | RAB9A (0.66) | RAB9AMAPTSMN1; SMN2TDP1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5021429-A | Histamine h2-antagonists; antisecretory-antiallergen agent; skin disorders and peptic ulcers | ALLEN & HANSBURYS LIMITED (GB) | 1991-06-04 | — | — | US | disclosed |