Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.59 |
| ▸ | MAPT | P10636 | 5/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | HEXA | P06865 | 2/20 | 0.45 |
| ▸ | HEXB | P07686 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.44 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dimethylamine SCHEMBL9871284 | 0.96 | RAB9A (0.54) | RAB9AMAPTSMN1; SMN2TDP1KMT2A | |
| Dimethylamine SCHEMBL9872141 | 0.94 | RAB9A (0.63) | RAB9AMAPTSMN1; SMN2TDP1KMT2A | |
| Dimethylamine SCHEMBL9871927 | 0.90 | MAPT (0.62) | RAB9AMAPTSMN1; SMN2TDP1KMT2A | |
| Dimethylamine SCHEMBL9871972 | 0.87 | RAB9A (0.57) | RAB9AMAPTSMN1; SMN2TDP1KMT2A | |
| SCHEMBL2202509 | 0.87 | RAB9A (0.57) | RAB9AMAPTSMN1; SMN2TDP1KMT2A | |
| SCHEMBL9127589 | 0.84 | RAB9A (0.63) | RAB9AMAPTSMN1; SMN2TDP1KMT2A | |
| Dimethylamine SCHEMBL9871769 | 0.84 | RAB9A (0.66) | RAB9AMAPTSMN1; SMN2TDP1KMT2A | |
| SCHEMBL9871916 | 0.83 | RAB9A (0.59) | RAB9AMAPTSMN1; SMN2TDP1KMT2A | |
| Hydrochloric Acid SCHEMBL9125718 | 0.83 | RAB9A (0.62) | RAB9AMAPTSMN1; SMN2TDP1KMT2A | |
| SCHEMBL2202629 | 0.83 | RAB9A (0.65) | RAB9AMAPTSMN1; SMN2TDP1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5021429-A | Histamine h2-antagonists; antisecretory-antiallergen agent; skin disorders and peptic ulcers | ALLEN & HANSBURYS LIMITED (GB) | 1991-06-04 | — | — | US | disclosed |